physiological changes Flashcards
haematological
increased circulatory volume- dilution leads to anaemia. reduced oncotic pressure leads to oedema and increased GFR. incr procoagulation factors and venous stasis so incr risk DVT
respiratory
increased tidal volume, incr CO2 levels to facilitate diffusion across the placenta
cardio
ESMs and 3rd heart sound common. JVP dilated but not raised. stroke vol and HR increased
gastro
reflux due to reduced LOS tone and abdominal compression
what is the pregnant woman more at risk with regards to anaesthesia
aspiration
liver
more clotting factors produced
kidneys
increased GFR- reductioons in urea, urate, creat. glycosuria common
uterus
increased blood flow, uterine artery hypertrophy, maturation.
what does progesterone secreted by the placenta do (>12 weeks)
reduce LOS tone, increase tidal volume, stop the menstrual cycle
what maintains corpus luteum and inhibits FSH/LH in early pregnancy
beta HCG
what is linea nigra
oestrogen stimulates melanocytes to deposit more melanin. in the midline as more melanocytes here
what is striae gravidarum
oestrogen causes break down of elastin
what is increased demand by the fetus
calcium- for skeletal growth