antiphospholipid syndrome Flashcards
diagnosis
antibodies on 2 tests 8 weeks apart +- past arterial thrombosis, venous thrombosis, recurrent pregnancy loss
diagnosis
antibodies on 2 tests 8 weeks apart +- past arterial thrombosis, venous thrombosis, recurrent pregnancy loss
antibodies in APS
lupus anticoagulant or anticardiolipin
what could APS follow
SLE
if untreated how many pregnancies make it to live birth
what can happen in APS in pregnancy
thrombosis of the placenta leading to insufficiency, IUGR death
management in pregnancy
regular fetal assessment from 20 weeks, medical
what drugs should be given
from conception- aspirin 75mg daily and heparin from 6 weeks to 34 weeks (throughout if prev thrombosis)
should you continue heparin/warfarin postpartum
yes risk is high- neither is CI in breastfeeding
antibodies in APS
lupus anticoagulant or anticardiolipin
what could APS follow
SLE
if untreated how many pregnancies make it to live birth
what can happen in APS in pregnancy
thrombosis of the placenta leading to insufficiency, IUGR death
management in pregnancy
regular fetal assessment from 20 weeks, medical
what drugs should be given
from conception- aspirin 75mg daily and heparin from 6 weeks to 34 weeks (throughout if prev thrombosis)
