Obstetric Cholestasis Flashcards

1
Q

incidence

A

0.1-0.5% all pregnancies

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2
Q

features

A

pruritis especially of the palms and soles in 2nd half pregnancy

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3
Q

tests

A

liver transaminases are mildly high, incr bilirubin in some

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4
Q

what does it increase risk of

A

pre term labour, fetal distress, stillbirthn

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5
Q

what can be given to treat

A

ursodeoxycholic acid- reduces pruritus and abnormal LFTs

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6
Q

what should be given to mother and baby at birth

A

vitamin K

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7
Q

what is contraindicated after

A

combined pill (oestrogen containing)

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8
Q

how often can this recur

A

40% pregnancies

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