Physiologic & Pharmacologic Actions Flashcards
Garlic
Anti-microbial. Reduce atherosclerotic lesions. Increase fibrinolysis, inhibit platelet aggregation, lower blood pressure/vasodilator
Ginkgo
Scavenge free radicals, open blood vessels, increase hypoxia tolerance, reduce retinal edema/lesions, improve memory/learning, inhibit platelet activation factor (PAF)
Onion
Antibacterial, lipid-reducing, antihypertensive, platelet-aggregation-inhibiting
Oat Bran
Lower cholesterol
Guar Gum
Lower cholesterol levels 6-8% and triglycerides 13-17% using 15g/day. Bind lipids
Red Yeast Rice
Inhibit HMG CoA—rate-limiting enzyme in cholesterol synthesis.
Aloe vera
Laxative (aloe latex). Gel: anti-inflammatory, wound healing
Calendula
Stimulate blood vessel growth
Chamomile
Anti-inflammatory, anti-spasmodic, carminative. Bacteriostatic, fungistatic
Comfrey
Demulcent, wound healing
Witch Hazel
Astringent, local anti-inflammatory
Tea Tree oil
antiseptic
Evening primrose oil
Provide GLA, bypassing delta 6 desaturase enzyme function.
Arnica
Antimicrobial, anti-inflammatory, respiratory stimulant, positive inotropic, uterine toner
Bromelain
Anti-inflammatory, anti exudative, prolong prothrombin time
Boswellia (Frankincense)
Anti-inflammatory
Capsicum
Initial reddening, pain, warmth followed by desensitization of nerve fibers
Devils Claw
Bitter tonic, antipyretic, analgesic, weak anti-inflammatory
Feverfew
Inhibit serotonin release form platelets. Antipyretic, toothache, headache,.
Willow Bark
Pain relief (analgesic), anti-inflammatory
Kava
Muscle relaxant, anticonvulsant, protective vs. strychnine poisoning. Reduce excitability of limbic system, neuroprotective vs. infarct. Local anesthetic (peripheral). Inhibit MAO-B. Interact w/ GABA-A receptor
Lavender
Potentiates GABA-A, inhibits spontaneous motor activity, sedative
Passion Flower
Reduce spontaneous locomotor activity
St. John’s Wort
Reuptake inhibition for: norepinephrine, 5-HT, dopamine. MAO inhibition, 5-HT1 activation. Down-reg: beta & DR1. Up-reg 5-HTR, alpha1; CYP3A4
Valerian
Indian & Mexican var higher valpotriates. Valerenic acid may decrease GABA degradation. Calming effect. Anti-convulsant. Insomnia? Glutamine->GABA
Wormwood, Aka absinthe
Bitter.