Physics Flashcards
Appropriate target range for medical audit:
Recall rate?
4-7%
My note: Prometheus says 4-7 in one place, 5-7 in another, and “less than 10%” in another.
Appropriate target range for medical audit:
Cancers/1000 screened?
3-8
How often:
Processor QC
Daily
How often:
Darkroom Cleanliness
Daily
How often:
Viewbox Conditions?
Weekly
How often:
Phantom Evaluation?
Weekly
How often:
Repeat Analysis?
Quarterly
How often:
Compression Test?
Semi-Annually
How often:
Darkroom Fog?
Semi-Annually
How often:
Screen-Film Contrast?
Semi-Annually
Places that do mammo have to be “accredited and certified”…..and pay money…. every _________.
3 years
_______ is the evil overlord begins the MQSA.
The FDA
Gaining the privilege to read mammograms: 3 criteria you must meet
1) read 240 mammography exams over 6 months during last 2 years of training, under direct supervision,
2) 3 months of mammography in residency,
3) 60 documented hours of mammo education
Spatial Resolution (mammo):
LP/mm in Anode-Cathode Direction ?
13 LP/mm
Spatial Resolution (mammo):
LP/mm in left-right Direction ?
11 LP/mm
Spatial Resolution (mammo):
MQSA resolution for screen-film: _____
12 LP/mm
Spatial Resolution (mammo):
MQSA resolution for digital: _____
Manufacturer specs (~ 7 LP/mm)
What is the MQSA breast dose phantom?
MQSA has breast phantom which is supposed to be an “average breast.”
- 4.2 cm of compressed breast
- 50% adipose, 50% glandular.
Dose for MQSA phantom
Phantom limit (per image)=
3 mGy (300 millirads) WITH GRID
1 mGy WITHOUT GRID.
Note: Dose limit ONLY for phantom!!! There is no regulation for dose to real human breast.
How Often:
Localization/Accuracy (for Stereotactic Biopsy)?
Daily before patient exams
Mammography facilities are required to provide patients with a “lay report”
- what is it?
- when does it need to be provided?
- written results of the mammogram in language that is easy to understand.
- within 30 DAYS of the study (MUST).
Consumer complaint mechanism is required to be established in mammography facilities to provide patients with a process for addressing their concerns.
.
Patients can have their ORIGINAL mammograms (not just copies) when they are needed.
.
If a facilities mammograms are determined to be substandard and a risk to public health, what happens?
Those FACILITIES will notify patients and their doctors and suggest an appropriate plan of action.
Who is ultimately responsible for the Quality Control program?
The “INTERPRETING PHYSICIAN”
Not the techs.
To make it (the phantom?) pass image quality, must show: _____(4 distinct things)
- 4 fibers
- 3 microcalcification clusters,
- 3 masses
- only “acceptable artifacts”
Patient dose limit in mammography
THERE IS NONE!
Only a dose limit for phantom (3 mGy/view). But a denser real breast could require more than 3 mGy/view.
Typical patient and phantom doses (not limits).
~2 mGy/view
~4 mGy for a two-view screening exam
Typical (average) compressed breast is
_______ cm,
_______ % glandularity.
6cm,
15-20%
Digital systems generally use higher beam quality, which results in ______ doses.
Lower
Digital mammography does NOT use fixed dose (screen-film). Can use as much or as little radiation as deem appropriate.
.
Nukes QC: how often to check…
Constancy
(And “Dose should be within ___% of computed activity.”)
Daily
5% of computed activity
Checked with reference sources
Nukes QC: how often to check…
Linearity
Quarterly
Nukes QC: how often to check…
Accuracy
At installation of device AND
Annually
Nukes QC: how often to check…
Geometry
At installation of device AND
Any time you move device
Does it affect Spatial resolution or Contrast resolution?:
Focal spot
Spatial
Smaller spot= better
Does it affect Spatial resolution or Contrast resolution?:
Detector Width
Spatial
Smaller detector = better
Does it affect Spatial resolution or Contrast resolution?:
Nyquist Limitations “Sampling”
Spatial
Oversampling = better
Does it affect Spatial resolution or Contrast resolution?:
Reconstruction Filter
Spatial
Ex: bone “sharp” algorithm gives a higher spatial resolution.
Does it affect Spatial resolution or Contrast resolution?:
Number of x-rays (mAs, kV, pitch)
Contrast
More dose—less mottle—will improve contrast resolution
Does it affect Spatial resolution or Contrast resolution?:
Slice thickness
Contrast
Thicker = more x-ray quanta = less noise
Does it affect Spatial resolution or Contrast resolution?:
Reconstruction Method
Contrast
Iterative > Filtered Back
Does it affect Spatial resolution or Contrast resolution?:
Reconstruction Filter
Contrast
Soft tissue > bone
Choose Increase or Decrease for all:
Holding matrix size constant and DECREASING FOV will
_______ pixel size. This will
_______ spatial resolution, and
_______ contrast resolution.
DECREASE pixel size
INCREASE spatial resolution
DECREASE contrast resolution
(Less photons per box)
Choose Increase or Decrease for all:
Holding matrix size constant and INCREASING FOV will
_______ pixel size. This will
_______ spatial resolution, and
_______ contrast resolution.
INCREASE pixel size
DECREASE spatial resolution
INCREASE contrast resolution
(More photons per box)
Will it improve Axial, Lateral, or Elevation Resolution?:
Shorter pulses
Axial
Smaller spatial pulse length
Will it improve Axial, Lateral, or Elevation Resolution?:
Greater Damping “Low Q”
Axial
Shorter pulses
Will it improve Axial, Lateral, or Elevation Resolution?:
Higher frequency
Axial
Shorter wavelength
Will it improve Axial, Lateral, or Elevation Resolution?:
Narrowing the beam in the proximal field (adding an acoustic lens). Minimal necessary gain (gain widens the beam).
I.e. “Put the thing you want to look at in the focal zone.”
Lateral
Will it improve Axial, Lateral, or Elevation Resolution?:
Phased array with multiple focal zones
Lateral
Will it improve Axial, Lateral, or Elevation Resolution?:
Increasing the “line density” or lines per cm
Lateral
Will it improve Axial, Lateral, or Elevation Resolution?:
Use fixed focal length across the entire surface of the array (downside is partial volume effects)
Elevation
Will it improve Axial, Lateral, or Elevation Resolution?:
Minimize slice thickness— done by phase excitation of the outer to inner arrays
Elevation
Axial Resolution is dependent on ________
Spatial Pulse Length
Lateral Resolution is dependent on ________
Transducer Element WIDTH
Elevation Resolution is dependent on ________
Transducer element HEIGHT
Artifacts:
Reverberation—what causes it?
Two parallel highly reflective surfaces
My note: looks like description might have been cut off. May want to double check not missing something
Artifacts:
Comet tail—what causes it?
Two parallel highly reflective surfaces —closer together (<1/2 SPL)
Artifacts:
Ring Down Artifact —what causes it?
Fluid trapped between tetrahedron of air bubbles
Artifacts:
Mirror Image—what causes it?
Trapped behind a strong reflector
My note: not sure this is complete…
Artifacts:
Reverberation—what does it look like?
Multiple equidistantly spaced linear reflections.
Artifacts:
Comet tail—what does it look like?
Triangle (comet) shaped…
Artifacts:
Ring Down Artifact—what does it look like?
Parallel band extending posterior to a collection of gas
Artifacts:
Mirror image—what does it look like?
This is almost always shown with the liver on lung.
MRI: Choose Increased, Decreased, or No Effect for each category when you have the following modification:
Thicker Slices
- Signal to Noise
- Spatial Resolution
- Duration of Exam
INCREASED signal to noise,
DECREASED spatial resolution,
NO EFFECT on duration of exam
MRI: Choose Increased, Decreased, or No Effect for each category when you have the following modification:
Larger Field of View
- Signal to Noise
- Spatial Resolution
- Duration of Exam
INCREASED signal to noise,
DECREASED spatial resolution,
NO EFFECT on duration of exam
MRI: Choose Increased, Decreased, or No Effect for each category when you have the following modification:
Larger Matrix
- Signal to Noise
- Spatial Resolution
- Duration of Exam
DECREASED signal to noise,
INCREASED spatial resolution,
INCREASED duration of exam
MRI: Choose Increased, Decreased, or No Effect for each category when you have the following modification:
Greater Field Strength
- Signal to Noise
- Spatial Resolution
- Duration of Exam
INCREASED signal to noise
NO EFFECT on spatial resolution
NO EFFECT on duration of exam
MRI: Choose Increased, Decreased, or No Effect for each category when you have the following modification:
Greater Receiver Bandwidth
- Signal to Noise
- Spatial Resolution
- Duration of Exam
DECREASED signal to noise
NO EFFECT on spatial Resolution
DECREASED duration of exam
MRI: Choose Increased, Decreased, or No Effect for each category when you have the following modification:
Greater Transmit Bandwidth
- Signal to Noise
- Spatial Resolution
- Duration of Exam
INCREASED signal to noise,
DECREASED spatial resolution,
NO EFFECT on duration of exam
MRI: Choose Increased, Decreased, or No Effect for each category when you have the following modification:
More Excitations per Slice
- Signal to Noise
- Spatial Resolution
- Duration of Exam
INCREASED signal to noise,
NO EFFECT spatial resolution,
INCREASED duration of exam
MRI: Choose Increased, Decreased, or No Effect for each category when you have the following modification:
Utilizing Partial K Space Sampling
- Signal to Noise
- Spatial Resolution
- Duration of Exam
DECREASED signal to noise
NO EFFECT on spatial resolution
DECREASED duration of exam
Artifact: Aliasing
Direction?
Phase encoding
Artifact: Chemical Shift
Direction?
Frequency encoding
Artifact: Gibbs/Truncation
Direction?
Both phase AND frequency encoding
Artifact: Motion Artifact
Direction?
Phase encoding
Artifact: Zipper
Direction?
Phase encoding
Artifact: Aliasing
Does it make it better or worse if you
Increase the field of view?
Better
Artifact: Aliasing
Does it make it better or worse if you
Change the phase encoding direction
Better
Artifact: Aliasing
Does it make it better or worse if you
Smaller FOVs
Worse!
Artifact: Chemical Shift
Does it make it better or worse if you
Bigger Pixels
Better
Artifact: Chemical Shift
Does it make it better or worse if you
Fat suppression
Better
Artifact: Chemical Shift
Does it make it better or worse if you
Increase Receiver Bandwidth
Better
Artifact: Chemical Shift
Does it make it better or worse if you
Stronger magnetic field
Worse!
Artifact: Chemical Shift
Does it make it better or worse if you
Lower receiver bandwidth
Worse!
Artifact: Gibbs/Truncation
Does it make it better or worse if you
Bigger matrix
Better
Artifact: Gibbs/Truncation
Does it make it better or worse if you
Decrease bandwidth
Better
Artifact: Gibbs/Truncation
Does it make it better or worse if you
Decrease pixel size (increase PE Steps, decrease FOV)
Better
Artifact: Partial Volume
Does it make it better or worse if you
Decrease pixel size (increase PE Steps, decrease FOV)
Better
Artifact: Partial Volume
Does it make it better or worse if you
Thicker slices
Worse!
Artifact: Motion Artifact
Does it make it better or worse if you
Saturation pulses
Better
Artifact: Motion Artifact
Does it make it better or worse if you
Respiratory gating
Better
Artifact: Motion Artifact
Does it make it better or worse if you
Faster sequences (BLADE, PROPELLER)
Better
Artifact: Cross Talk
Does it make it better or worse if you
Increase slice gap
Better
Artifact: Cross Talk
Does it make it better or worse if you
Interleave slices
Better
Artifact: Field Inhomogeneity
Does it make it better or worse if you
Shimming
Better
Artifact: Field Inhomogeneity
Does it make it better or worse if you
GRE Sequences
Worse!
Artifact: Susceptibility
Does it make it better or worse if you
GRE Sequences
Worse!
Artifact: Eddy Current
Does it make it better or worse if you
Optimize sequence of gradient pulses
Better
Artifact: Eddy Current
Does it make it better or worse if you
DWI-large gradient changes
Worse!
Artifact: Dielectric Effects
Does it make it better or worse if you
Parallel transmit
Better
Artifact: Dielectric Effects
Does it make it better or worse if you
Use 1.5T
Better
Artifact: Dielectric Effects
Does it make it better or worse if you
3T
Worse!
Artifact: Magic Angle
Does it make it better or worse if you
T2
Better
Artifact: Magic Angle
Does it make it better or worse if you
T1, PD
Worse!
Artifact: Magic Angle
Cause?
Occurs at 55 degrees
Artifact: Dielectric effects
Cause?
Standing waves created as radiowave approaches length of body part
(My note: unclear if this is a cause or just trivia…they share a box in chart.)
Artifact: Eddy Current
Cause?
Caused by geometric distortion or non-uniformity
Artifact: Susceptibility
Cause?
Augmentation of magnetic field.
Trivia: very bad in EPI
Artifact: Field Inhomogeneity
Cause?
Geometric distortion
Artifact: Zipper
Cause?
Poor shielding
Artifact: Cross Talk
Cause?
Overlap of slices
Artifact: Gibbs/Truncation
Cause?
Limited sample of FID
Artifact: Gibbs/Truncation
Classic location?
Spinal cord
Artifact: Chemical Shift
Cause?
Differences in resonance frequencies
Artifact: Aliasing
Cause?
A small FOV
Major spill, how much is it?:
Tc-99m
100 mCi
[100 mCi : Tc99m, Tl-201;
10 mCi: In-111, Ga-67;
1 mCi: I-131 ]
Major spill, how much is it?:
Tl-201
100 mCi
[100 mCi : Tc99m, Tl-201;
10 mCi: In-111, Ga-67;
1 mCi: I-131 ]
Major spill, how much is it?:
In-111
10 mCi
[100 mCi : Tc99m, Tl-201;
10 mCi: In-111, Ga-67;
1 mCi: I-131 ]
Major spill, how much is it?:
Ga-67
10 mCi
[100 mCi : Tc99m, Tl-201;
10 mCi: In-111, Ga-67;
1 mCi: I-131 ]
Major spill, how much is it?:
I-131
1 mCi
[100 mCi : Tc99m, Tl-201;
10 mCi: In-111, Ga-67;
1 mCi: I-131 ]
Radionuclide Purity (Tc):
- what is it?
- how is it tested?
What: “How much Mo in the Tc?”
Tested: in a dose calibrator with lead shields
Chemical Purity (Tc):
- what is it?
- how is it tested?
What: how much Al in the Tc?
Tested: with pH paper
Radiochemical Purity (Tc):
- what is it?
- how is it tested?
What: How much free Tc?
Tested: thin layer chromatography
Acute Radiation Syndrome:
Bone marrow—dose needed?
> 2 Gy
[ Bone Marrow:
>2 Gy,
1-6 wk latent period,
Can live.]
Acute Radiation Syndrome:
Bone marrow—latent period?
1-6 weeks
[Bone Marrow:
>2 Gy,
1-6 wk latent period,
Can live.]
Acute Radiation Syndrome:
Bone marrow—outcome?
Worse with higher dose. It’s possible to survive.
[Bone Marrow:
>2 Gy,
1-6 wk latent period,
Can live.]
Acute Radiation Syndrome:
GI—dose needed?
> 8 Gy
[GI:
> 8 Gy,
5-7 day latent period,
death within 2 weeks.]
Acute Radiation Syndrome:
GI—latent period?
5-7 days
[GI:
> 8 Gy,
5-7 day latent period,
death within 2 weeks.]
Acute Radiation Syndrome:
GI—outcome?
Death with 2 weeks
[GI:
> 8 Gy,
5-7 day latent period,
death within 2 weeks.]
Acute Radiation Syndrome:
CNS—dose needed?
> 20-50 Gy
[CNS:
> 20-50 Gy,
4-6 hour latent period,
death within 3 days.]
Acute Radiation Syndrome:
CNS—latent period?
4-6 hours
[CNS:
> 20-50 Gy,
4-6 hour latent period,
death within 3 days.]
Acute Radiation Syndrome:
CNS—outcome?
Death within 3 days
[CNS:
> 20-50 Gy,
4-6 hour latent period,
death within 3 days.]
Acute Radiation sickness:
WB Dose: < 1 Gy
- Effect on GI
- Effect on skin
- Action needed
GI: no vomiting
Skin: no redness
Action: surveillance for 5 weeks
Acute Radiation sickness:
WB Dose: 1-2 Gy
- Effect on GI
- Effect on skin
- Action needed
GI: vomiting 2-3 hours after exposure
Skin: redness 12-24 hours after
Action: surveillance for 3 weeks, consider general hospital
Acute Radiation sickness:
WB Dose: 2-4 Gy
- Effect on GI
- Effect on skin
- Action needed
GI: vomiting 1-2 hours after
Skin: redness 8-15 hours after
Action: hospitalize - burn center
Acute Radiation sickness:
WB Dose: > 4 Gy
- Effect on GI
- Effect on skin
- Action needed
GI: vomiting < 1 hour after
Skin: redness 1-6 hours after
Action: hospitalize - Specialized radiation center
Transient equilibrium:
What is it?
Classic example?
How long until achieved? (In half lives)
Equilibrium that occurs when half life of the daughter is shorter than the parent (but not by a lot).
Classic example: Moly-99 generator making Tc-99.
A transient equilibrium happens after 4 half lives (usually).
Routine premedication:
2 methods
- drugs
- doses
- routes
- frequencies
Method 1: -prednisone, 50 mg, PO -13 hours, 7 hours, 1 hour (before contrast) -diphen (50 mg IV) 1 hour before (can PO)
Method 2: -methylprednisolone, 32 mg, PO -12 hours, 2 hours (before contrast) -diphen (50 mg IV) 1 hour before (can PO)
[NOTE: diphen present and EXACTLY same for ALL premeds.]
Emergent Premedication:
3 methods:
- drugs
- doses
- route
- frequency
Method 1: -methylprednisolone, 40 mg, IV OR hydrocortisone sod. succ., 200 mg, IV -q4 until contrast -diphen (50 mg IV) 1 hour before
Method 2: *If NSAID allergy or history asthma -dexamethasone sodium, 7.5 mg, IV OR Betamethasone, 6 mg, IV -Q4 until contrast -diphen (50 mg IV) 1 hour before
Method 3:
- If can’t give steroids—infection, risk of bowel perforation
- just diphen (50 mg IV) 1 hour before
[NOTE: diphen is present and EXACTLY same for all!]
Exposure Dose Limits:
Occupational workers:
Minimal age?
18 years
Exposure Dose Limits:
Occupational workers:
Lens?
150 mSv/yr
“(Some new papers say 20 mSv)”
Exposure Dose Limits:
Occupational workers:
Radiation worker?
50 mSv /yr
Exposure Dose Limits:
Occupational workers:
Extremity?
500 mSv/yr
Exposure Dose Limits:
Public Exposure:
Infrequent?
5 mSv/yr
Exposure Dose Limits:
Public Exposure:
Continuous ?
1 mSv/yr
Exposure Dose Limits:
Public Exposure:
Embryo/fetus via MOTHER?
5 mSv/yr (1 mSv to fetus directly)
Exposure Dose Limits:
Public Exposure:
Embryo Fetus (post declared pregnancy)?
0.5 mSv/MONTH
Exposure Dose Limits:
Public Exposure:
Controlled areas?
50 mSv/yr
Exposure Dose Limits:
Public Exposure:
Uncontrolled areas?
5 mSv/yr
Exposure Dose Limits:
Public Exposure:
Genetically Significant Dose?
0.25 mSv
Exposure Dose Limits:
Public Exposure:
Effective dose from background radiation in US?
3 mSv/yr
Package labels: what does it mean??
WHITE 1
- special handling?
- surface dose rate?
- 1 meter dose rate?
no special handling
Surface: < 0.5 mrem/hr
1 meter: 0 mrem/hr
Package labels: what does it mean??
YELLOW 2
- special handling?
- surface dose rate?
- 1 meter dose rate?
-special handling, yes
Surface: < 50 mrem/hr
1 meter: < 1 mrem/hr
Package labels: what does it mean??
YELLOW 3
*bc the assholes couldn’t choose another color
- special handling?
- surface dose rate?
- 1 meter dose rate?
Special handling, yes
Surface: < 200 mrem/hr
1 meter: < 10 mrem/hr
MRI
2D Table Time formula
Time=TR x Phase Matrix x NEX
TR: time between each RF pulse (usu in milliseconds)
Phase Matrix: data the system collects from each phase encoding step
NEX: number of times each set of phase encoding steps is repeated (Number of EXcitations)
MRI
3D Table Time Formula
(Note: unless they specify 3D in question, you should assume it’s 2D).
Time=TR x Phase Matrix x NEX x # Slices!!!
[slices # is what’s different from 2D!]
TR: time between each RF pulse (usu in milliseconds)
Phase Matrix: data the system collects from each phase encoding step
NEX: number of times each set of phase encoding steps is repeated (Number of EXcitations)
MRI
Better Spatial Resolution if:
Small or Large VOXEL?
SMALL voxel
MRI
Better Spatial Resolution if:
Small or Large FIELD OF VIEW?
SMALL Field of view
MRI
Better Spatial Resolution if:
Smaller or Larger MATRIX?
LARGER matrix
MRI
Better Spatial Resolution if:
Thinner or Thicker SLICES?
THINNER slices
MRI
Better Spatial Resolution if:
“Steep (Large) Slice Selection Gradient, and Thin Transmit Bandwidth”
.
MRI
Better SNR if:
Weaker or Stronger magnet?
STRONGER magnet
MRI
Better SNR if:
Short or Long TR?
LONG TR
MRI
Better SNR if:
Small or Big FOV?
BIG FOV
MRI
Better SNR if:
Small or Large SLICES?
LARGE slices
MRI
Better SNR if:
Less or More NEX?
MORE NEX
MRI
Better SNR if:
Short or Long TE
SHORT TE
MRI
Better SNR if:
Small or Large Matrix?
SMALL Matrix
MRI
Better SNR if:
Small or Large Receiver Bandwidth?
SMALL Receiver Bandwidth
MRI
Better SNR if:
_______ COIL SIZE
Appropriate
MRI
Better SNR if:
“Shallow (small) slice selection gradient, and Thick transmit bandwidth”
.
MRI, Potential Fuckery:
Terms that sound very similar!
Fat Receiver Bandwidth = _____ SNR
Fat TRANSMIT Bandwidth = _____ SNR (Small or Large slice?)
Fat Receiver Bandwidth =DECREASE SNR
Fat TRANSMIT Bandwidth = Large slice= Increased SNR
MRI, Potential Fuckery:
Terms that sound very similar!
Narrow Receiver Bandwidth = _____ SNR
Narrow TRANSMIT Bandwidth = _____ SNR (Small or Large slice?)
Narrow Receiver Bandwidth = INCREASED SNR
Narrow TRANSMIT Bandwidth = Small/Thin slice = DECREASED SNR