PHYSICAL EXAM PART 2 Flashcards
• A form of factitious disorder where a person fabricates or induces an
illness to assume the patient role
MUNCHAUSEN SYNDROME
MUNCHAUSEN SYNDROME
• One method:
• Variation:
tampering with laboratory specimens
Munchausen syndrome by proxy
Examples: artifactual/factitious hematuria (common), factitious
proteinuria
MUNCHAUSEN SYNDROME
• Be aware of highly variable results and/or incompatible biochemical
profiles
• In the absence of lab workflow errors, consider sample manipulation
MUNCHAUSEN SYNDROME
• May be reported as clear, hazy/slightly cloudy, cloudy, turbid, or
milky
URINE CLARITY
• Refers to the transparency or turbidity of a specimen
URINE CLARITY
• Freshly voided urine is usually…
•_____ urine is NOT always normal
CLEAR
• Precipitation of phosphates and carbonates may cause…
white
cloudiness
•____ should correspond with the amount of material observed under the microscope
Clarity
NON-PATHOLOGIC TURBIDITY
• Presence of…
squamous epithelial cells and mucus
• Specimens allowed to stand or that are refrigerated
• White precipitate in alkaline pH:________
• Pink precipitate in acidic pH:______
amorphous phosphates and carbonates
amorphous urates
• Semen, spermatozoa, prostatic fluid
• Fecal contamination
NON-PATHOLOGIC TURBIDITY
• Radiographic contrast media: contrast materials used in x-rays and CT scans; high SG (_____)
> 1.040
• Talcum powder
• Vaginal creams
NON-PATHOLOGIC TURBIDITY
PATHOLOGIC TURBIDITY
• Red blood cells
• White blood cells
• Bacteria
• Yeast
• Abnormal amounts of non-squamous epithelial cells
• Trichomonads
• Abnormal crystals
• Lymph fluid: chyluria in filariasis (lymph fluid leaking into kidneys)
• Lipids
• Calculi
• Measures the kidney’s ability to concentrate glomerular filtrate by tubular reabsorption
SPECIFIC GRAVITY
SG
Methods
•_____: buoyancy
•_____: refractive index
•_____: sound waves
•_____: colligative properties
•_____: change in pH
Urinometry
Refractometry
Harmonic oscillation densitometry
Osmolality
Reagent strip
ODOR
•: odorless to aromatic
Freshly voided urine
• Not fresh urine: ODOR
ammoniacal (due to the breakdown of ammonia)
• Bacterial infections: ODOR
strong, unpleasant
• Ketones: ODOR
sweet or fruity
• MSUD:ODOR
maple syrup
• Phenylketonuria:ODOR
mousy
• Tyrosinemia:ODOR
rancid butter
• Isovaleric acidemia:ODOR
sweaty feet
• Methionine malabsorption:ODOR
cabbage, hops
• Trimethylaminuria:ODOR
rotting fish
ODOR: contamination
Bleach