Phys Blood Pressure Flashcards
___ is the primary mechanism involved in short term regulation of arterial BP.
It is a ____ system. What happens when MAP increases/decreases?
Baroreceptor reflex
Negative feedback
Increase: symp incr, parasymp decr
Decrease: opposite
Where are baroreceptors found? What kind of receptors are they?
Carotid sinuses
Aortic arch
Large vessels in the thorax
*stretch receptors
The ___ baroreceptors are tonically active. They are the most sensitive and effective baroreceptors, so the ___ are not as sensitive
Carotid sinus
Aortic arch baroreceptors
Baroreceptors display both ___ and ___ characteristics. Explain each
- Tonic: magnitude of BP (MAP)
2. Phasic: rate of change in BP
If arterial pressure is elevated for a period of time the baroreceptor output will be ____
*shifts to the ___
Lower
Right
Peripheral resistance:
Pressor vs depressor center
- P: tonically active, controls symp outflow - changes TPR
2. D: not tonically active, modulates activity of pressor center, indirectly affects TPR
Cardiac output:
Cardioinhibitory system vs. Cardiostimulatory system
- I: tonically active, controls parasympathetic output to heart
- S: tonically active, controls symp output to heart
Afferent pathway
Vagus n.
Glossopharyngeal n.
Efferent pathway
Sympathetic
Parasympathetic
Decreased pressure leads to ____
Increased pressure leads to ____
Increased SNS output
Decreased SNS output
Effector organs in the baroreceptor reflex
- Heart: rate and contractility (output)
- Arteriolar smooth muscle: resistance
- Venular smooth muscle: capacitance
- Adrenal medulla: EPI and NEPI release
Low pressure baroreceptors are located where?
Right atrium
Pulmonary a.
Changes in central venous pressure are relayed to the ___ and on to the ___ to alter sympathetic and parasympathetic activity
Hypothalamus
Cardioinhibitory/stimulatory centers
Receptors involved in sympathetic system
- Alpha 1 on vascular smooth muscle
- Beta 1 on myocardium and kidney
- Beta 2
Receptors involved in parasympathetic system
- M
- Craniosacral outflow- vasodilation
- NO