Medi - Hypertension And Hyperlipidemia Flashcards
Definition of hypertension
SBP>140
DBP>90
Prehypertension
Stage 1
Stage 2
P: 120-139, 80-89
1: 140-159, 90-99
2: >160, >100
SBP >140 with normal DBP
Isolated systolic hypertension
Elevated BP due to stress of doctors office
White coat hypertension
Hypertension with no specific identifiable cause
Essential/primary/idiopathic
Severe hypertension without symptoms
Hypertensive urgency
Uncontrolled hypertension causing acute end organ dysfunction
Hypertensive emergency
Severe hypertension with retinal changes or papilledema
Malignant hypertension
Every ____ increase in systolic or ___ increase in diastolic BP ____ the risk of heart disease
20
10
Doubles
MAP =
CO =
MAP = CO x SVR CO = SV x HR
There is often an increased ___ tone in hypertensive patients
Sympathetic
- Alpha 1 receptors
- Alpha 2 receptors
- Beta 1 receptors
- Beta 2 receptors
- Vasoconstriction of mooth muscle cells
- Inhibits NE release, negative feedback
- Increases chronotropy, inotropy, and renin release
- Epi causes vasodilation
The most common cause of secondary hypertension is
Renal parenchymal disease
Who should be treated for hypertension?
- <60 y/o with BP of 140/90 or higher
- > 60 with bp of 150/90 or higher
- Diabetic or those with CKD with BP 140/90 or higher
Initial treatment for black vs. non black patients
B: CCB or thiazide
N: ACEI, ARB, Thiazide or CCB
Treatment for Patients over 18 with CLD
ACEI or ARB
Common side effects of thiazide diuretics
Increased urinary freq
Hypokalemia
Electrolyte imbalances
*because they inhibit Na and Cl reabsorption
Common side effects of ACEI
Renal insufficiency
Hyperkalemia
Cough
Tx for;
- Hypertension with CKD
- Hypertension with CHD
- ACEI and ARB
2. ACE/ARB + diuretics + beta blocker
Examples of high intensity statins
Atorvastatin (40 or 80mg)
Rosuvastatin (20 or 40mg)
* greater than 50% reduction in LDL
Ezetimibe causes ___
60% decrease in intestinal cholesterol absorption
Flushing is a common side effect of ___
Niacin
Start moderate intensity statins at what risk?
5%
CV risk calculator factors
Diabetes Age Smoking status Hypertension HDL