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MSK 2 > Pharmacology - Topical Medications > Flashcards

Pharmacology - Topical Medications Flashcards

1
Q

which of these is a liquid and good for large skin area application

a.lotions
b.ointments
c.creams
d.gels
e.paste
f.powder
g.patches

A

a.lotions

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2
Q

which of these is paraffin based and is a barrier for skin protection

a.lotions
b.ointments
c.creams
d.gels
e.paste
f.powder
g.patches

A

b.ointments

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3
Q

which of these is oil / water based with emulsifiers

a.lotions
b.ointments
c.creams
d.gels
e.paste
f.powder
g.patches

A

c.creams

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4
Q

which of these is alcohol based and liquifies on contact with skin

a.lotions
b.ointments
c.creams
d.gels
e.paste
f.powder
g.patches

A

d.gels

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5
Q

which of these is a thicker mix of powdered rug and ointment

a.lotions
b.ointments
c.creams
d.gels
e.paste
f.powder
g.patches

A

e.paste

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6
Q

which molecules are more readily absorbed and and are able to diffuse through the dermis to deeper tissues and blood vessels

a.large polar
b.small non polar

A

b.small non polar

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7
Q

which type of molecule is better for drugs being topically administered for systemic effect eg transdermal opioids

a.large polar
b.small non polar

A

b.small non polar

which molecules are more readily absorbed and and are able to diffuse through the dermis to deeper tissues and blood vessels

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8
Q

which type of molecule is better for drugs being topically administered to act on the epidermis eg topical antifungals

a.large polar
b.small non polar

A

a.large polar

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9
Q

fentanyl and buprenorphine are example of ……. opioids

A

topical

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10
Q

it may take un to 12 hours for transdermal opioid to get to full analgesic opiod effect so a short acting opiod may be required at the start , how long does transdermal opiod continue to have effect for after removal of the patch

a.6 hours
b.12 hours
c.24+ hours
d.6 months

A

c.24+ hours

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11
Q

in order for transdermal opioids to be appropriate pain levels need to be

a.erratic
b.stable

A

b.stable
transdermal route too slow for frequent adjustments

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12
Q

which transdermal opiod is better in renal impairment

a.fentanyl
b.buprenorphine
c.morphine

A

a.fentanyl

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13
Q

which topical opioid is better tolerated in those with cognitive impairment

a.fentanyl
b.buprenorphine

A

b.buprenorphine

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14
Q

in which case is it useful to give transdermal NSAIDs eg diclofenac

A

patients with inflammatory conditions who are too high risk for systemic NSAID therapy
eg renal, cvs, gi

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15
Q

what is used local anaesthetic lidocaine topically used for

A

IV lines In peads

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16
Q

which local anaesthetic blocks voltage gated sodium channels and nociceptive signals from skin

a.diclofenac
b.buprenorphine
c.lidocaine
d.novocane

A

c.lidocaine

17
Q

which channels does local anaesthetic lidocaine block

a.voltage gated sodium
b.voltage gated calcium
c.GABA A
d.Dopamine 2
e.Potassium channels

A

a.voltage gated sodium

18
Q

lidocaine patches are sometimes used in ……….. neuralgia

a.trigemeninal
b.occipital
c.postherpetic

A

c.postherpetic

Post-herpetic neuralgia is a lasting pain in the areas of your skin where you had shingles

19
Q

uses of topical corticosteroids

A

inflammatory skin conditions
eczema dermatitis dermatoses
where simple emollients have been innefective

20
Q

which type of topical corticosteroids is best for moist/weeping lesions

a.water miscible creams
b.ointments
c.lotions

A

a.water miscible creams

21
Q

which type of topical corticosteroids is best for dry scaly lesions

a.water miscible creams
b.ointments
c.lotions

A

b.ointments

22
Q

which type of topical corticosteroids is best for large areas especially hairy areas

a.water miscible creams
b.ointments
c.lotions

23
Q

where should highly potent steroids eg beclomethasone, dermovate , diprosone, elocon be avoided

a face and skin extensors
b.face and skin flexures
c.hands and feet

A

b.face and skin flexures

can cause skin thinning

24
Q

hydrocortisone is an example of which potency of corticosteroid

a.mild
b.moderate
c.potent
d.very potent

25
Q

eumovate is an example of which potency of topical corticosteroid

a.mild
b.moderate
c.potent
d.very potent

A

b.moderate

26
Q

betnovate,diprosone,elocon are examples of which potency of topical corticosteroids

a.mild
b.moderate
c.potent
d.very potent

27
Q

dermovate is an example of which potency of topical corticosteroid

a.mild
b.moderate
c.potent
d.very potent

A

d.very potent

28
Q

1% drug is how many g/ 100 ml water

A

1g/100 ml
1000mg/ 100ml
10mg/ml

MSK 2 (16 decks)

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