Pharmacology: Recreational Drug Intoxication/Withdrawal Flashcards
Cocaine and Amphetamine: MOA
NE/DA reuptake inhibitor
Ecstasy: MOA
Alters 5-HT release and reuptake
Hallucinogens: MOA
Alterations and 5-HT functioning
PCP/Ketamine: MOA
NMDA Antagonists
Marijuana: MOA
Activates cannabinoid receptors and increase dopamine
Benzodiazepines: MOA
GABA agnoists
Gammahydroxybutyrate (GHB): MOA
Altered DA transmission, GABA analog
Inhalants: MOA
CNS depression via inhibitory neurotransmitters
Treatment for drugs that are more than just supportive (all of them have supportive as tx)
Cocaine/Amphetamine
- Lorazepam for agitation, Haloperidol for psychotic agitation, and dopamine agonist for extreme cravings.
Benzodiazepines
- Give flumazenil (short acting benzodiazepine) for acute OD, longer acting benzodiazepine for chronic use
GHB
- Consider benzodiazepines