Pharmacology: Autism Spectrum Disorder

Question 1

Medications are helpful in treating ________ symptoms

Answer 1

Behavioral (not social or communication symptoms)

Question 2

Antipsychotics are used to treat ________ and ________.

Answer 2

irritability and aggression

Question 3

Atypical Antipsychotics used for ASD:

Answer 3

Risperidone and Ariprprazole (FDA APPROVED)

Question 4

Risperidone and Aripiprazole: MOA

Answer 4

D2 and 5-HT 2A receptor Antagonists

Question 5

Risperidone and Aripiprazole: Therapeutic Use

Answer 5

Irritability and Aggression.

Question 6

Typical Antipsychotics used for ASD:

Answer 6

Chlorpromazine and Haloperidol (FDA APPROVED)

Question 7

Chlorpromazine and Haloperidol: MOA

Answer 7

D2 Antagonist only

Question 8

Chlorpromazine and Haloperidol: Therapeutic Use

Answer 8

For more severe behavioral problems in children. Limited use due to significant adverse effects.

Question 9

Antidepressants used for ASD:

Answer 9

SSRIs and TCAs (Tricyclic Antidepressants): Not really focused on it seems like. TCAs have more adverse effects while data on SSRI use is limited.

Question 10

Therapeutic Use for Antidepressants

Answer 10

Concern with suicidal ideation

Question 11

1st line therapy for ASD:

Answer 11

Atypical Antipsychotics