Pharmacology - Pain Mgmt Flashcards
Explain the MOA behind Fentanyls rapid onset
Fentanyl is very lipophilic, and rapidly crosses the BBB into the CNS, resulting in rapid onset ( appx 30 sec-min)
Fentanyl is _____ more potent than morphine.
80-100 x
Explain mechanism of low dose Ketamine for pain
Ketamine’s MOA is dose dependent
- Low dose = analgesia
- High dose = dissociative anesthetic
For the patient who has a hx of opioid abuse or chronic pain experiencing acute pain (like from an extremity fracture), it is (appropriate/inappropriate) to treat with opioids.
appropriate
- it is an acute injury
The geriatric may have difficulty receiving adequate analgesia. Why?
Expression:
- cognitive difficulties expressing themselves
- “stoic” manner
Physical signs:
- Other meds may mask “signs” of objective pain like tachycardia
- May have changes to their metabolism of meds
Sedation and analgesia may overlap. Why?
Sedation meds will reduce agitation 2/2 pain. It will increase cooperation to interventions.