Pharmacology - Pain Mgmt Flashcards

1
Q

Explain the MOA behind Fentanyls rapid onset

A

Fentanyl is very lipophilic, and rapidly crosses the BBB into the CNS, resulting in rapid onset ( appx 30 sec-min)

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2
Q

Fentanyl is _____ more potent than morphine.

A

80-100 x

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3
Q

Explain mechanism of low dose Ketamine for pain

A

Ketamine’s MOA is dose dependent

  • Low dose = analgesia
  • High dose = dissociative anesthetic
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4
Q

For the patient who has a hx of opioid abuse or chronic pain experiencing acute pain (like from an extremity fracture), it is (appropriate/inappropriate) to treat with opioids.

A

appropriate

- it is an acute injury

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5
Q

The geriatric may have difficulty receiving adequate analgesia. Why?

A

Expression:

  • cognitive difficulties expressing themselves
  • “stoic” manner

Physical signs:

  • Other meds may mask “signs” of objective pain like tachycardia
  • May have changes to their metabolism of meds
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6
Q

Sedation and analgesia may overlap. Why?

A

Sedation meds will reduce agitation 2/2 pain. It will increase cooperation to interventions.

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