Pharmacology of the NMJ Flashcards

1
Q

tetradotoxin action and origin

A

comes from puffer fish

blocks diffusion of Na through Na channel, thus prevent depolarization and propagation of AP in nerve cells

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2
Q

toxicity of tetradotoxin

A

all secondary to blockade of AP

acts on CNS and PNS

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3
Q

bupivacaine MoA

A

produces complete sensory block

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