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CR > pharmacology of the airways > Flashcards

pharmacology of the airways Flashcards

1
Q

what are the 2 zones of the airways called

A

conducting and respiratory

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2
Q

which post-ganglionic parasympathetic nerve fibres cause bronchoconstriction
what receptor

A

cholinergic M3

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3
Q

which post-ganglionic nerve fibres cause bronchodilation
what receptor

A

NANC, NO receptor

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4
Q

what are the Ach related bronchodilator medicine

A

M3 antagonists (SAMA and LAMA) eg iprotropium(SAMA) glycopyrronium(LAMA)

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5
Q

what is the first line of treatment for asthma

A

ICS

BROWN!!!!!! beclometasone

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6
Q

how does ICS work

A

interfering with HAT and HDAC
pro-inflammatory genes switched off
anti-inflam genes switched on

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7
Q

what is 1st line treatment for COPD

A

LABA or LAMA

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8
Q

give some examples of pro-inflam mediators

A

IL6 CLCX-8

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9
Q

which IG meidates allergy

A

IgE

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10
Q

what happens when Ig pathway is set into action with allergy

A

mast cell degranulation

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CR (12 decks)

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