kidneys

Question 1

what % CO goes to the kidneys

Answer 1

20

Question 2

what is normal eGFR

Answer 2

90ml/min

Question 3

how is eGFR calculated?

Answer 3

based on serum creatinine, adjusted for age, ethnicity, sex

Question 4

what is a classic sign of CKD

Answer 4

elevated proteinuria

Question 5

why is the PCT full of mitochindria

Answer 5

need ATP for na/k atpase pump to get reabsorption of glucose, AA’s etc by facilitated diffusion with Na+

Question 6

describe the loop of Henle and what happens

Answer 6

thin descending limb - water out
thick ascending limb impermeable to water, NaCl goes out

Question 7

describe the loop of Henle and what happens

Answer 7

thin descending limb - water out
thick ascending limb impermeable to water, NaCl goes out

Question 8

The maintenance of what important homeostatic feature happens in the loop of Henle. How?

Answer 8

acid base balance
HCO3 can be reabsorbed into blood and H+ can be pumped into the lumen by Na+ antiporter

Question 9

what enzyme speeds up the H2O + CO2 <-> HCO3- + H+ reaction

Answer 9

carbonic anhydrase

Question 10

outline the most common buffer system in the body

Answer 10

H2O + CO2 <->
H2CO3 <->
HCO3- + H+

Question 11

what is pH proportional and inversely proportional to

Answer 11

proportional to HCO3
inv proportional to pCO2

Question 12

what is pAO2

Answer 12

partial pressure of alveolar O2

Question 13

what is paO2

Answer 13

partial pressure of arterial O2