Pharmacology (Inhalation Agents) Flashcards
1
Q
What are the MACs of anesthestics
A
iso = 1.15 sevo = 1.71 des = 6 N20 = 104
2
Q
What increases MAC?
A
hyperthermia
hypernatremia (due to possible interactions with NA channels)
chronic ETOH ingestion
RED HAIR
drug induced elevations in central catecholamines (SSRIs may, but its not in the books)
1-6 months of age, (Sevo is only 1-2 months)
3
Q
What decreases MAC?
A
hypothermia hyponatremia pregnancy lithium lidocaine neuraxial opioids PaO2
4
Q
NO Change in MAC
A
Duration of anesthesia Hyper or hypokalemia Anesthetic metabolism Thyroid gland dysfunction (IF in euthyroid state) Gender PaCO2 15-95 mmHg PaO2 > 38 mmHg SBP > 40 mmHg
