Pharmacology in Breastfeeding Flashcards
What are the benefits of breastfeeding for the baby?
Reduced risk of infections, neurological development, protection against developing atopic diseases, lower incidence of insulin dependant diabetes and lower risk of SIDS
What are the benefits of breastfeeding for the mother?
Reduction in risk of pre-menopausal breast, ovarian cancer and hip fractures
Less uterine bleeding, prevents post-natal depression, contraception and faster weight loss
What are some drugs which should be avoided while breastfeeding?
Cytotoxic, immunosuppressants, anti-convulsant, recreational drugs, amiodarone, lithium and radio-iodine
What is the adverse effect of tetracycline during breastfeeding?
Risk of permanent tooth staining in infant
What is the adverse effect of isoniazid during breastfeeding?
Risk of pyridoxine deficiency in the infant
What is the adverse effect of barbiturates during breastfeeding?
Lethargy, sedation and poor suck reflexes
What is the adverse effect of choral hydrate during breastfeeding?
Drowsiness if infant fed at peak
What is the adverse effect of diazepam during breastfeeding?
Drug accumulation and sedation
What is the adverse effect of methadone during breastfeeding?
Risk of withdrawal if breast feeding stops
What is the adverse effect of iodine during breastfeeding?
Thyroid suppression and risk of cancer
What is the adverse effect of propylthiouracil during breastfeeding?
Can suppress thyroid function in infant
What drug can suppress lactation?
Cabergoline
Which drug can enhance lactation?
Metoclopramide
10mg 2-3 times daily
Also domperidone is an option
What are the principles of prescribing in breastfeeding?
Avoid unnecessary drug use
If safe for use in paediatrics/ neonates then likely safe in breastfeeding
Try to choose drugs with pharmacokinetic properties to reduce baby’s exposure to drug
What can be given for lower back pain when breastfeeding?
Topical NSAIDs
Paracetamol, ibuprofen and dihydrocodeine
