Embryology - 3 Flashcards
Where does the kidneys, ureter and gonads arise from?
Intermediate mesoderm
What is the urogenital ridge?
Nephrogenic cord and the gonadal ridge
Part of urinary system and reproductive system develop from this
What does the urogenital ridge differentiate into?
Gonadal ridge medially which gives rise to gonad and nephrogenic cord laterally to form kidneys and ureter
When does the urinary system develop?
Ahead of repro system
From 4th week of embryo development
What 2 overlapping systems in nephrogenic cord does the kidney and ureter develop from?
Pronephros, mesonephros and metanephros
Describe the course of the kidneys when developing
Develop in pelvis then ascend into abdomen with the final position taken by 12 week
Where is the bladder and urethra developed from?
Urogenital sinus (part of cloaca) which also gives rise to female and male repro tracts
What are the 3 stages of development of the nephrogenic cord?
Pronephros - non functional
Mesonephros - functional but transient
Metanephros - final kidney
What does the metanephric mesenchyme form?
Kidneys
What does the ureteric duct form?
Ureter
What does the nephric duct drain into?
Cloaca - common temporary outlet for digestive, urinary and genital tract in embryonic life
What are some types of renal anomalies?
Renal agenesis
Horseshoe kidney
Pelvic kidney
Duplex kidney
Duplex ureter and calyceal system
What is the cloaca?
Caudal end of the enfolded yolk sac
Covered by cloacal membrane
What forms the cloaca?
Fusion of the ectoderm and endoderm
What is formed from the urorectal septum dividing the cloaca?
Urogenital sinus and anal canal