Pharmacology Exam 2 Flashcards

1
Q

What does CNS stand for?

A

Central Nervous System

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2
Q

What is the Somatic Nervous System responsible for?

A

Sensory and motor movement

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3
Q

What are the two divisions of the Autonomic Nervous System?

A

Sympathetic - fight and flight; Parasympathetic - rest and digest

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4
Q

What are the 7 areas affected by the nervous system?

A

BP, HR, RR, Temp, Water balance, Urinary excretion, Digestive function

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5
Q

What is the primary function of Beta 1 receptors?

A

Heart/cardiac

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6
Q

What is the primary function of Beta 2 receptors?

A

Lungs - vasodilation

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7
Q

What effects do Alpha 1 receptors have?

A

Blood vessels - vasoconstriction, iris dilation, bladder closure

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8
Q

What is the function of Alpha 2 receptors?

A

Insulin release

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9
Q

What are the effects of a sympathetic response?

A

Increased BP, Increased HR, Bronchodilation, Decreased bowel sounds

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10
Q

What is the neurotransmitter and receptor of the PNS?

A

Cholinergic drugs - Acetylcholine

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11
Q

What is the neurotransmitter and receptor of the SNS?

A

Adrenergic drugs - Norepinephrine

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12
Q

What are Muscarinic receptors responsible for?

A

Pupil constriction, GI motility, increase bladder contraction, saliva, slow heart rate, in some vascular smooth muscle

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13
Q

What are Nicotinic receptors responsible for?

A

Skeletal system; muscle contraction

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14
Q

What do adrenergic blocking agents do?

A

Block effects of sympathetic nervous system, block norepinephrine from receptor site, decrease BP, decrease HR, increase renal perfusion

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15
Q

What is myasthenia gravis?

A

Chronic muscular disease caused by a defect in neuromuscular transmission of voluntary muscles (Tensilon diagnostic)

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16
Q

What drug is used for Alzheimer’s?

A

Donepezil (indirect cholinergic agonist)

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17
Q

What is Dobutamine?

A

Beta and Alpha Adrenergic Agonist (IV) - management of HF by increasing myocardial contractility

18
Q

What is Dopamine used for?

A

Beta and Alpha Adrenergic Agonist (IV) - management of shock, increased BP, HR, and improved renal flow

19
Q

What is Epinephrine used for?

A

Beta and Alpha Adrenergic Agonist (IV, IM, SQ, Nebulizer) - management of shock, allergic reactions, asthma attacks

20
Q

What is Norepinephrine used for?

A

Beta and Alpha Adrenergic Agonist (IV) - management of shock, increases BP

21
Q

What is Phenylephrine used for?

A

Alpha Specific Adrenergic Drug - management of hypotension, increases BP by constricting blood vessels

22
Q

What is Midodrine used for?

A

Alpha Specific Adrenergic Drug - management of hypotension, increases BP by constricting blood vessels

23
Q

What is Clonidine used for?

A

Alpha Specific Adrenergic Drug - management of hypertension, decreases BP and HR

24
Q

What is Isoproterenol used for?

A

Beta Specific Adrenergic Drugs (IV) - treats shock, bradycardia, heart blocks

25
What is Albuterol used for?
Beta Specific Adrenergic Drugs (MDI) - treatment of bronchospasms, bronchodilation
26
What is Terbutaline used for?
Beta Specific Adrenergic Drugs (PO, SQ) - treatment of asthma, COPD, bronchodilation
27
What is Carvedilol?
Non-selective adrenergic blocking agent (PO) - treatment of hypertension and CHF
28
What is Labetalol?
Non-selective adrenergic blocking agent (PO, IV) - treat hypertension, decreases BP
29
What is Amiodarone?
Non-selective adrenergic blocking agent (PO,IV) - first-line cardiac life support medication
30
What is Phentolamine?
Non-selective alpha antagonist - increases vasodilation
31
What is the suffix of alpha1 drugs used to treat hypertension?
'-Zosin'
32
What is Propranolol?
Non-selective Beta Adrenergic blocking agent (PO) - treatment of HTN, angina, palpitations, stage fright
33
What is Timolol?
Non-selective Beta Adrenergic blocking agent (PO, gtts) - HTN, decrease intraocular pressure
34
What is Atenolol?
Beta1-Selective Adrenergic blocking agent (PO,IV) - MI, angina, HTN
35
What is Metoprolol?
Beta1-Selective Adrenergic blocking agent (PO,IV) - prevention of reinfarction post MI, angina, HTN
36
What is Bethanechol?
Direct cholinergic Agonist (PO) - treats urinary retention
37
What is Neostigmine?
Indirect cholinergic Agonist (SQ, IM) - diagnosis and management of myasthenia gravis
38
What is Pyridostigmine?
Indirect cholinergic Agonist (PO) - long term management of myasthenia gravis
39
What is Edrophonium?
Indirect cholinergic Agonist (IVP) - Diagnostic agent for myasthenia gravis
40
What is Atropine?
Anticholinergic (blocking) Drug - treat bradycardia, dry secretions, dilate pupils
41
What do anticholinergic drugs do?
Decrease GI activity and secretion
42
What are the side effects of anticholinergic drugs?
Hot, dry, blind, red, mad