Pharmacology - Drugs (protein, lipoprotein, drug enzymes and drug membranes)

Question 1

Give 3 examples of drugs that bind to protein or lipoprotein receptors.

Answer 1

SALBUTAMOL

• Stimulates ca2+ influx to smooth muscles. Produces bronchodilation to help with patients with asthma.

INSULIN

• G protein receptor site. Contracts the iris dilator and therefore pupils open up.

ATROPINE

• Blocks G - protein mediated ion channel activity. Relax muscles inside the eye so stop one focussing when undertaking refraction.

Question 2

Give 3 examples of drugs that bing to enzymes.

Answer 2

PYRIDOSTIGMINE

• Interactions with enzymes that break down the neurotransmitters. To improve brain function in the elderly and controls muscle tone in the weak muscles. (MG)

IBUPROFEN

• Interactions with the enzyme controlling tissue inflammation. Controls inflammation.

PENICILLIN

• Works as an anti-bacterial drug.

Question 3

Give 3 examples of drugs that bind to membranes.

Answer 3

TETRACAINE

• Blocks na + channels to stop pain transmission. Anaesthetics such as eyedrops.

HYPERTONIC SALINE

• exert osmotic pressure across the membrane. Is a diuretics - so promotes fluid output.

POLYMYXIN B

• The action of the drug makes the membrane leaky to ions.