Pharmacology - Drugs (Adrenergic, Gaba)

Question 1

Give an example of a direct acting adrenergic drug that binds to a alpha1 receptor?

Answer 1

PHENYLEPHRINE

• works at smooth muscles and is used as a nasal decongestant for colds and flus.

Question 2

Give an example of a direct acting adrenergic drug that binds to beta1 receptors?

Answer 2

EPHEDRINE

• controls respiration and blood pressure. Used to improve breathing in in asthma.

Question 3

Give an example of a direct acting adrenergic drug that binds to peripheral alpha2 receptors?

Answer 3

APRACLONIDNE

• used as eyedrops to reduce intraocular pressure.

Question 4

Give an example of a direct acting adrenergic drug that binds to peripheral beta2 receptors?

Answer 4

EPINEPHRINE

• Relaxes trachobranical system to promote opening up of airways. Helps breathing.

SALBUTAMOL

• Used in patients with asthma to help breathing.

Question 5

Give an example of an indirect acting adrenergic drug that has multiple actions.

Answer 5

VENLAFAXINE

• is a SNRI, a serotonin and norepinephrine reuptake inhibitor. Anti - depressant.

DULOXETINE

• is a noradrenaline/5 HT re uptake inhibitor. Used as an anti depressant and other stress related conditions.

Question 6

Give an example of an indirect acting adrenergic drug that inhibits MAO.

Answer 6

PHENELZINE

• is a MAOI. Anti depressant.

Question 7

Give an example of an illegal indirect acting adrenergic drug.

Answer 7

COCAINE

• promotes unregulated release. Used as a high.

Question 8

Give an example of a direct acting adrenergic blocking drug with alpha1 receptors.

Answer 8

PRAZOSINE

• blocks peripheral alpha1 receptors. Used to reduce blood pressure.

Question 9

Give an example of a direct acting adrenergic blocking drug with beta receptors.

Answer 9

PROPRANOLOL

• blocks both beta1 and beta2 receptors which will reduce pulse. Used to lower blood pressure.

Question 10

Give 2 examples of direct acting gabaergics

Answer 10

DIAZEPAM

• benzodiazepines. Used for a sedative effect for pre surgery and also used for anti anxiety drugs.

NITRAZEPAM

• Used as ‘strong’ sleep aids or as an anti-anxiety drug.

Question 11

Give 2 examples of indirect acting gabaergics.

Answer 11

VIGBATRIN

• Inhibits GABA - T to selectively increase GABA in frontal lobe. Used as an Anti epileptic Drug in children and adults.

VALPROIC ACID

• Also promotes GABA release. Used as a AED.

Question 12

Give an example of a direct and indirect GABA drug?

Answer 12

ETHANOL (alcohol)

• A CNS depressant that promotes relaxation. Causes sedation at high doses.