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CP > Pharmacology (Drugs) > Flashcards

Pharmacology (Drugs) Flashcards

1
Q

Give an example of a drug which will block 5-lipoxygenase pathways

A

Montelukast or Zafirlukast

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2
Q

Give an example of a drug which through regular use can reduce bronchial reactivity but should only be used prophalactically

A

Sodium cromoglicate or Nedocromil Sodium

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3
Q

What is the name of the Monoclonal antibody to IgE

A

Omalizumab

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4
Q

Give 2 anti-IL-5 drugs

A

Mepolizumab or Reslizumab

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5
Q

Give 2 anti-IL-13 drugs

A

Tralokinumab or Lebrikizumab

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6
Q

What corticosteroid should be used to treat mild athsma daily?

A

Beclomethasone

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7
Q

What corticosteroid should be used to treat stronger athsma daily?

A

Fluticasome

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8
Q

What oral corticosteroid should be used to treat severe athsma and how is it taken?

A

Prednisolone is taken orally

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9
Q

What IV corticosteroid should be used to treat severe athsma?

A

Hydrocortisone

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10
Q

Give an example of an anti muscarinic

A

Ipratorpium, Oxitropium, Tiotropium, ect

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11
Q

Give 2 examples of B2 agonists

A

Salbutamol and Salmeterol

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12
Q

Give 3 examples of PDE inhibitors used for COPD and asthma

A

Theophylline, aminophylline or Roflumilast

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13
Q

Give a β-adrenoceptor antagonist used to treat Hypertension

A

Atenolol

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14
Q

Give a α-adrenoceptor antagonist

A

Doxazosin

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15
Q

Give a α₂-adrenergic agonist

A

Clonidine

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16
Q

Give 2 examples of ACE inhibitors

A

Ramipril, Captopril

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17
Q

Give 2 angiotensin II receptor antagonists

A

Candesartan, Iosartan

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18
Q

Give 2 Thiazide diuretics

A

Bendroflumethazide and metolazone

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19
Q

Give 2 Loop diuretics

A

Furosemide, Bumetanide

20
Q

Why would you use a loop diuretic over a thiazide diuretic?

A

Loop Diuretics are better suited in more extreme cases of pulmonary oedema while Thiazide diuretics are more prophylactic

21
Q

Give 2 potassium-sparing diuretics

A

amiloride, spironolactone

22
Q

Give an example of a K+-sparing diuretic

A

Co-amilofruse

23
Q

Give an example of a Calcium channel antagonist

A

amlodipine, verapamil

24
Q

Give 2 examples of potassium channel openers

A

minoxidil and Verapamil

25
Q

What cardiac glycoside is recommended for use in heart failure?

A

Digoxin

26
Q

What Pulmonary Vasodilator should be used in heart failure?

A

Milrinone, it is a PDE inhibitor

27
Q

What B-adrenoceptor antagonist can be used in cases of heart failure?

A

Bisoprolol

28
Q

What drugs can be used to inhibit platelet aggregation in acture coronary syndrome?

A

Aspirin, clopidogrel, dipyridamole, abciximab

29
Q

Why may an LMW heparin be used over a unfractionated heparin?

A

Longer half life

30
Q

Give 2 examples of LMW Heparins

A

Enoxaparin, Dalteparin

31
Q

Gove an example of a Direct thrombin inhibitor you can use kn Acute Coronary syndrome

A

Dabigatran

32
Q

Give an example of a Direct factor X inhibitor used in Acute Coronary Syndrome

A

Rivaroxaban

33
Q

Give an example of a Vitamin K antagonist

A

Warfarin

34
Q

What are Vitamin K antagomists used for?

A

Used as anticoagulants

35
Q

Give 3 examples of thrombolytics used in actue coronary sydrome

A

Streptokinase, alteplase, tenecteplase

36
Q

When should thrombolytics be used?

A

To break up clots which are blocking affected arterys

37
Q

Give 3 examples of statins

A

Simvastatin, Atorvaststin, Rosuvaststin

38
Q

Give 2 examples of Fibrates

A

Fenofibrate, gemfibrozil

39
Q

What do fibrates do?

A

Lower triglyceride levels in the blood

40
Q

Give examples for drugs in each of the 4 classes of anti-arrhythmic drugs

A

Class 1: lidocaine
Class 2: Bisoprolol or Atenolol
Class 3: amiodarone
Class 4: amlodopine

41
Q

What are the 4 classes of anti-arrhythmic drugs?

A

Class 1: Sodium channel blockers
Class 2: Beta Blockers
Class 3: potassium channel blockers
Class 4: calcium channel blockers

42
Q

Give 2 Anti-histamines

A

Chlorphenamine, Cetrizine

43
Q

Give 2 examples of Opioids used for cough suppression

A

Dextromethorphan and Codeine

44
Q

What antidepressants works to cure smoking addiction and how?

A

Bupropion acts as an inhibitor of dopamine reuptake increasing permanent conc of dopamine.

Varenicline works as a partial agonist at central nicotine’s receptors, competing for nicotine receptor binding and decreasing do-amine produced

45
Q

What

A

CP (9 decks)

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