Pharmacology: diuretics(hypertension) Flashcards

1
Q

what are the 3 different types of diuretics

A

thiazide, loop and K-sparing

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2
Q

give an example of a thiazide diuretic

A

bendroflumethiazide

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3
Q

give an example of a loop diuretic

A

furosemide

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4
Q

give an example of a K-sparing diuretic

A

spironolactone

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5
Q

describe the action of thiazide diuretics

A

inhibit Na + Cl reabsorption in distal convoluted tubules and are vasodilators

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6
Q

what effect do thiazide diuretics have an diuresis

A

less potent diuresis

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7
Q

describe the action of loop diuretics

A

block Na-K-2Cl symporter in the ascending loop of Henle and are venodilators

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8
Q

what effect do loop diuretics have on diuresis

A

induce potent diuresis

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9
Q

give 2 side effects of loop diuretics

A

hypokalaemia and hyperuricaemia

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10
Q

when should caution be taken with loop diuretics

A

in gout and diabetes

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11
Q

describe the action of K-sparing diuretics

A

aldosterone antagonists

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12
Q

what is there of a risk of in K-sparing diuretics

A

hypokalaemia

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13
Q

give a side effect of K-sparing diuretics

A

gynaecomastia

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