Pharmacology: diuretics(hypertension) Flashcards
what are the 3 different types of diuretics
thiazide, loop and K-sparing
give an example of a thiazide diuretic
bendroflumethiazide
give an example of a loop diuretic
furosemide
give an example of a K-sparing diuretic
spironolactone
describe the action of thiazide diuretics
inhibit Na + Cl reabsorption in distal convoluted tubules and are vasodilators
what effect do thiazide diuretics have an diuresis
less potent diuresis
describe the action of loop diuretics
block Na-K-2Cl symporter in the ascending loop of Henle and are venodilators
what effect do loop diuretics have on diuresis
induce potent diuresis
give 2 side effects of loop diuretics
hypokalaemia and hyperuricaemia
when should caution be taken with loop diuretics
in gout and diabetes
describe the action of K-sparing diuretics
aldosterone antagonists
what is there of a risk of in K-sparing diuretics
hypokalaemia
give a side effect of K-sparing diuretics
gynaecomastia