Pharmacology: Calcium channel blockers(hypertension)

Question 1

what type of Ca channels do they block

Answer 1

L type

Question 2

what are the 2 different types of Ca channel blocker

Answer 2

dihydropyridines

non-dihydropyridines

Question 3

give an example of a dihydropyridine Ca channel blocker

Answer 3

amlodipine

Question 4

give an example of a non-dihydropyridine Ca channel blocker

Answer 4

verapamil

Question 5

give the name of the drug that acts as both a dihydropyridine and non-dihydropyridine

Answer 5

diltiazem(benzothiapezine)

Question 6

what effect do dihydropyridines have

Answer 6

vasodilators

Question 7

what effect do non-dihydropyridines have

Answer 7

a negative inotropic and chronotropic effect

Question 8

give 3 side effects of Ca channel blockers

Answer 8

peripheral oedema(ankle swelling)
dizziness
flushing

Question 9

what other type of drug should non-dihydropyridines be avoided using with

Answer 9

beta blockers

Question 10

what location of Ca channels are dihydropyridines more selective for

Answer 10

L-type channels in the smooth muscles(peripheral vasodilator)

Question 11

what location of Ca channels are non-dihydropyridines more selective for

Answer 11

for SA and AV node