Pharmacology: Chapter 12 Drugs for the Tx of Cardiovascular Disease Flashcards

1
Q

Cardiovascular Disease

A

Disease of the heart and blood vessels

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2
Q

What are the different diseases associated with Cardiovascular Disease?

A
Hypertension
Angina Pectoris
Coronary Heart Disease
Arrhythmia's
Heart Failure (HF)
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3
Q

Patients who have suffered an MI (Myocardial Infarction) should wait for ___ before receiving any type of oral health care

A

6 months

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4
Q

Heart Failure (HF)

A

Where the heart cannot pump efficiently, not being able to meet the bodies needs

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5
Q

What is Starlings Law?

A

Where the heart becomes enlarged to produce a more efficient heartbeat and cardiac output

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6
Q

Treatment of Heart Failure is indicated by?

A

American Heart Association (AHA) and the stage of HF and whether the patient has any comorbid conditions

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7
Q

At what stage of HF is it incredibly important to discuss risk factor reduction and to educate the patient and their family?

A

Stage A

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8
Q

What are the main actions of Digoxin?

A

To increased the force and strength of contraction of the myocardium (Positive inotropic effect)

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9
Q

What local anesthetics should be used with caution in a patient that takes Digoxin?

A

Anesthetic with Vasoconstrictor to reduce arrythmias

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10
Q

What are the signs of overdose in a patient that is taking Digoxin?

A

Nausea
Vision Changes
Copious Salivation

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11
Q

Define Arrythmia/Dysarrythmia

A

abnormal heart rhythm, used interchangeably

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12
Q

What should you check when working with patients that are taking antiarrhythmic medications?

A

Check for abnormal or extra heart beats when taking blood pressure and pulse

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13
Q

What should you check in patients who are taking Warfarin?

A

Their INR (The pharmacologic ratio that dictates how long it takes the patient to form a clot)

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14
Q

What is the most common side effect in a patient taking a Calcium Channel Blocker (CCB)?

A

Gingival enlargement

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15
Q

Define Angina Pectoris

A

A common cardiovascular disease that is characterized by pain or discomfort in the chest radiating to the left arm and shoulder

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16
Q

What is hypertension?

A

Diagnosed High Blood Pressure
THE SILENT KILLER
Most Common Cardiovascular Disease

17
Q

What is considered HBP?

A

BP that is higher than 130/80

18
Q

What is Essential Hypertension?

A

90-95% of patients have this

Familial

19
Q

What is Secondary Hypertension?

A

Approximately 10% of patients
Associated with a specific disease process involving the endocrine or renal system
Can be eliminated by removing the cause

20
Q

What is Malignant Hypertension?

A

BPs are very high and rapidly rising

Usually evidence or Retinal or Renal damage

21
Q

What are the big four antihypertensive groups?

A

Diuretics
Angiotensin Converting Enzyme Inhibitors (ACEIs)
Angiotensin Receptor Blockers (ARBs)
Calcium Channel Blockers (CCBs)

22
Q

What is hyperlipidemia?

A

Elevations of plasma lipid concentrations above accepted normal values

23
Q

LDL?

A

Bad cholesterol, Because excess deposits of cholesterol are placed in artery walls and considered the most dangerous

24
Q

HDL?

A

Good cholesterol, because they carry cholesterol away from the blood vessels

25
What are the drugs of choice to treat patients with atherosclerotic heart disease and elevated cholesterol values?
HMG CoA Reductase Inhibitors "Statins"
26
What is an anticoagulant?
Drugs that interfere with coagulation and prevent clotting
27
What is hemostasis?
the body's normal function to prevent loss of blood after injury to a blood vessel by clot formation
28
Warfarins pharmacologic effect is ___ when therapy begins
Delayed
29
The maximum effect of Warfarin take place after ____?
(5) half lives
30
Warfarin is monitored by?
International Normalized Ratio (INR) A function of prothrombin time (PT) of the patient, how long it takes blood to clot