Pharmacology

Question 1

First order kinetics

Answer 1

• Rate of clearance as same as rate of concentration in the body

Question 2

Zero order kinetics

Answer 2

• Drug is eliminated at a constant rate regardless of drug concentration
• Like aspirin

Question 3

Drugs that pass into the breast milk

Answer 3

• NSAIDS
• MTX
• Leflunomide
• Steriods (if more than 20 mg per day, wait 4 hours)

Question 4

Drugs that are okay during breastfeeding

Answer 4

• Anti TNF
• Plaquenil
• AZA
• Cyclosporine
• Sulfasalazine

Question 5

What illnesses can predispose to Reye;s?

Answer 5

• Aspirin with flu and varicella

Question 6

Drug interactions of NSAIDS

Answer 6

• MTX

- Warfarin (can displace from protein binding site and increase its effects)