Pharmacology Flashcards

1
Q

What is pharmocology

A

The study of drug action

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are 3 main ways of naming drugs

A

Chemical name
Generic name
Trade name

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the types of drugs that produce an effect due their physiochemical property

A
  • antacids
  • osmotic diuretics
  • general anaesthetic
  • osmotic laxatives
  • bulk laxatives
  • alcohol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Give an example of antacids

A

Sodium bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Give an example of bulk laxatives

A

Methycellulose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Give an example of osmotic laxatives

A

Magnesium sulfate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Give an example of osmotic diuretics

A

Mannitol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Give and example of general anaesthetic

A

Halothane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the 3 characteristics of a drug

A
  • potency
  • specificity : chemical and biological
  • stereo selectivity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is a high potency of a dug

A

When a high effect is produced even though not all the drugs are bound to a receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How do drugs bind a receptor

A

Lock and key hypothesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is a drug

A

A substance that acts on a biological system to change it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Name 3 endogenous agonist

A
  • acetylcholine
  • histamine
  • TNF
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Name 3 antagonist

A
  • atropine
  • anti histamine
  • etanercept
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the two quantitative pharmacology assumption

A
  • drug+ receptor gives the effect

- number of drugs is fixed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is EC50

A

The concentration of the agonist which produces half the response

17
Q

What is EMAX

A

The maximal response produced from an agonist

18
Q

What is the dissociation constant

A

EC50

19
Q

What is the equation for the dissociation constant

A

[A][R]/[AR]

20
Q

Why is the dissociation constant used

A

To calculate the drug action without having to produce a agonist/response curve experimentally