Pharmacology Flashcards
(46 cards)
Where the dose is increasing sharply
Therapeutic range
Which scheduled drug is highest abuse potential, no accepted medical use
Schedule I
Which scheduled drug is high abuse potential, written prescription with signature only, no refills
Schedule II
Which scheduled drug is moderate abuse potential, may phone in, five RX in six months
Example: Tylenol #3
Schedule III
Which scheduled drug has lower abuse potential, may phone in, five Rx in six months
Example: Valium (diazepam) and Darvon
Scheduled IV
Which scheduled drug lowest abuse potential, some may be available OTC
Scheduled V
The pharmacological activity of a drug, related to dose
The amount of drug necessary to produce an effect
Potency
Potency is GREATER when dose is ____
SMALLER
Maximum response of a drug, regardless of the dose
Efficacy
The time it takes for the drug to have an effect
Onset
The length of time that a drug has an effect
Duration
One measure of duration
The amount of time necessary for a drug to fall 1/2 of its original blood level
Half life
The route of administration affects both what?
onset and duration
Two major groups of routes of drug administration
Enteral
Parental
What type of administration that is placed directly into the GI tract
oral route
Rectal route
Enteral
Which type of administration bypasses the GI tract
IV,IM, SQ, intradermal, Inhalation, topical, sublingual
Parenteral
This administration is safest, least expensive and most convenient.
Large area for absorption (small intestine)
Oral route
This administration produces MOST RAPID drug response, best for emergency situations
IV (intravascular)
This administration provides sustained effect
massaging muscle will increase the drug’s absorption
Deltoid or gluteal muscles common injection sites
IM (intramuscular)
Insulin is administered this way?
SQ (subcutaneous)
This provides rapid delivery across large surface area of respiratory mucosa
Asthma inhalers and nitrous oxide/oxygen sedation
Inhalation
Drug applied to a body surface (skin, mucosa)
Most effective in non-keratinized areas
Topical
What is the study of how a drug enters the body, circulates in the body, and leaves the body
Pharmacokinetics
ADME
absorption, distribution, metabolism, elimination