Pharmacology

Question 1

Agonist

Answer 1

• Drug that enhances effect of a neurotransmitter

Question 2

Antagonist:

Answer 2

• Drug that inhibits effect of a neurotransmitter

Question 3

Competitive Binding:

Answer 3

• Binds to same binding site as neurotransmitter
• Can be antagonist or antagonist
• Binds to orthosteric site

Question 4

Noncompetitive Binding:

Answer 4

• Binds to a different site
• Can be another neurotransmitter that is not the primary neurotransmitter
• Bind to allosteric site (not binding site of neurotransmitter)
• Called neuromodulators or allosteric modulators
• Usually enhance or diminish function of neurotransmitter

Question 5

Amino Acid Neurotransmitter:

Answer 5

• Fast acting
• Direct synapses
• i.e. glutamate, GABA, Glycine, Aspartate

Question 6

Monoamine Neurotransmitter:

Answer 6

• Synthesized from one amino acid

* Localized

Question 7

Catecholamines

Answer 7

• Synthesized from tyrosine
o i.e. dopamine, norepi, epi
o Tyrosine-> L-Dopa->Dopamine->Norepinephrine->Epinephrine

Question 8

Idol amines

Answer 8

• Synthesized from Tryptophan

o i.e Serotonin