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USMLE Step 1: Things I Cannot Remember > Pharmacology > Flashcards

Pharmacology Flashcards

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USMLE® Step 1 flashcards
1
Q

Drugs that cause SLE-like syndrome:

A

SHIPPE

  1. Sulfa drugs
  2. Hydralazine
  3. Isoniazid
  4. Procainamide
  5. Phenytoin
  6. Etanercept
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2
Q

Sulfa drugs:

A
  1. Probenecid
  2. Furosemide
  3. Acetazolamide
  4. Celecoxib
  5. Thiazides
  6. Sulfonamides (antibiotics)
  7. Sulfasalazine
  8. Sulfonylureas
  • Mneumonic: Popular FACTSSS
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3
Q

What is the treatment with cyanide toxicity?

A

Nitrate + thiosulfate, hydroxycobalamin

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4
Q

Antidote for acetaminophen toxicity:

A

N-acetylcysteine (replenishes glutathione)

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5
Q

Antidote for amphetamines:

A

NH4Cl to acidify urine

  • because amphetamines make urine more basic
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6
Q

Antidote for antimuscarinics, anticholinergics:

A
  • Anitmuscarinics: physostigmine salicylate
  • Anticholinergics: control hyperthermia
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7
Q

How do you reverse benzodiazepine toxicity?

A

flumazenil!

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8
Q

Antidote for ß-blocker toxicity:

A

glucagon

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9
Q

Treatment for CO poisoning:

A

100% O2, hyperbaric O2

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10
Q

What is used to treat Cu, Ag and arsenic poisoning?

A

penicillamine

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11
Q

What is used to reverse heparin?

A

protamine sulfate

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12
Q

What is used for Fe poisoning?

A

Deferoxamine, deferasirox

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13
Q

What is the treatment for Pb poisoning?

A

EDTA, dimercaprol, succimer, penicillamine

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14
Q

What is used for Mercury poisoning?

A

dimercaprol (BAL), succimer

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15
Q

What is the treatment for methemoglobinemia?

A

methylene blue, vit C

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16
Q
  1. What is the treatment for salicylate toxicity?
  2. What is the treatment for TCA toxicity?
A
  1. Salicylate toxicity: NaHCO3 (alkalinize urine), dialysis
  2. TCA toxicity: NaHCO3 (plama alkalinization)
17
Q

How do you reverse the effects of tPA/streptokinase/urokinase?

A

aminocaproic acid

18
Q

What is the treatment to reverse the effects of warfarin?

A
  • Immediate effect: fresh frozen plasma
  • Delayed effect: Vitamin K

USMLE Step 1: Things I Cannot Remember (16 decks)

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