Neurology Flashcards
1
Q
What passes through the cribiform plate?
A
CN I
2
Q
Superior orbital fissure:
A
- CN III
- CN IV
- CN V1
- CN VI
- Opthalmic vein
- Sympathetic fibers
3
Q
Foramen rotundum:
A
CN V2
4
Q
Foramen ovale:
A
CN V3
5
Q
Foramen spinosum:
A
Middle meningeal artery
6
Q
What do CN II - VI pass through?
A
Middle cranial fossa — through spenoid bone
7
Q
Optic canal:
A
- CN II
- Opthalmic artery
- Central retinal vein
8
Q
Internal auditory meatus:
A
- CN VII
- CN VIII
9
Q
Jugular foramen:
A
- CN IX
- CN X
- CN XI
- Jugular vein
10
Q
What does CN XII pass through?
A
Hypoglossal canal
11
Q
Foramen magnum:
A
- CN XI (spinal roots)
- Brain stem
- Vertebral arteries
12
Q
STURGE-Weber syndrome:
A
Congenital, non-inherited developmental anomaly of neural crest derivatives (mesoderm/ectoderm):
- Sporadic, port-wine Stain (CN V1/V2 distribution)
- Tram-track calcifications
- Unilateral
- Retardation
- Glaucoma; GNAQ gene (activating mutation)
- Epilepsy
13
Q
Tuberous sclerosis:
A
HAMARTOMAS:
- Hamartomas (CNS & skin)
- Angiofibromas
- Mitral regurgitation
- Ash-leaf spots
- Rhabdomyoma (cardiac)
- (Tuberous sclerosis)
- autosomal dOminant
- Mental retardation
- renal Angiolipoma
- Seizures; Shagreen patches
- increase incidence of subependymal astrocytomas & ungual fibromas
14
Q
NF1 (von Recklinghausen disease):
A
Mutated NF1 tumor suppressor gene (neurofibromin, negative regulator of RAS) on chromosome 17:
- Cafe-au-lait spots
- Lisch nodules (iris hamartomas)
- Cutaneous neurofibromas (neural crest derived)
- Optic gliomas
- Pheochromocytomas
15
Q
von Hippel-Lindau disease:
A
deletion of VHL gene (tumor suppressor) on chromosome 3:
- Hemangioblastomas (retina, brain stem, cerebellum, spine)
- Angiomatosis
- Renal cell carcinomas (bilateral)
- Pheochromocytomas
