Pharmacology Flashcards
Name the SSRI drugs using the acronym:
Effective
For
Sadness
Panic
Compulsions
Effective - escitalopram (lexapro)
For - Fluoxetin (prozac)
Sadness - Sertraline (zoloft)
Panic - Paroxetine (Paxil)
Compulsions - Citalopram (Celexa)
What is the function of SSRI drugs?
To block the reabsorption of serotonin in the brain to treat depression.
SSRI’s major side effects are known as the 3 S’s. What are they?
S - Stomach upset
S - Sexual dysfunction
S - Serotonin syndrome
What other drug combinations can cause serotonin syndrome?
Most common:
SSRI + SSRI
SSRI + SNRI
SSRI + MAOI
Less common:
SSRI + triptans
SSRI + lithium
SSRI + levodopa
What are the symptoms of serotonin syndrome?
Delerium, agitation, tachycardia (rapid heart rate), diaphoresis (excessive sweating), diarrhea, seizures
What is the treatment for serotonin syndrome?
- Stop offending medications
- IV fluids
- Cyproheptadine to lower serotonin production
- Benzodiazepine to lower muscle rigidity
Which are the following foods you should avoid if taking MAOI drugs?
A. Tyramine rich foods (cheese, pickled foods, wine)
B. Purine rich foods (anchovies, sardines, alochol)
C. Fast Foods
A. Tyramine foods
MAOIs reduce the body’s ability to break down dietary amines and can lead to a hypertensive crisis.
What are the 3 types of drug names?
- Chemical name (N-acetyl-parap-aminophenol)
- Genetic name (acetaminophen)
- Trade name (Tylenol)
A drug can have multiple _________ names but only one _______ name.
Trade, Generic
Example: Ibuprofen (generic) has multiple trade names (Advil, Motrin, etc)
What are the 4 main parenteral (outside of the GI tract) ways that drugs are administered?
Intravenous, Intramuscular, Subcutaneous, Intrathecal
Drug names that end with -tidine are for what kind of medications?
Histamine 2 blocker/acid reducers (Cimetidine)
Drug names that end with -prazole are for what kind of medications?
Protein pump inhibitor/acid reducers (Omeprazole)
Drug names that end with -cillin are for what kind of medications?
Penicillin antibiotic family (Amoxicillin)
Drug names that end with -floxicinare for what kind of medications?
Tetracycline antibiotic family (Tetracycline)
Drug names that end with -thromycin are for what kind of medications?
Macrolide antibiotic family (Azithromycin)