Pharmacology Flashcards

1
Q

State the mechanism of action of quinolones

A

Inhibit DNA synthesis by creating mutations to DNA gyrase, which reduce intracellular quinolone concentration.

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2
Q

61 year-old woman with a history of cardiac problems develops hearing loss after a prolonged admission in hospital. Which drug may cause this?

A

Aminoglycosides ( eg. Gentamicin ), furosemide, aspirin, cytotoxic agents.

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3
Q

Which drugs can cause erythema nodosum?

A

Penicillins
Sulphonamides
COCP

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