Pharmacology Flashcards
1
Q
State the mechanism of action of quinolones
A
Inhibit DNA synthesis by creating mutations to DNA gyrase, which reduce intracellular quinolone concentration.
2
Q
61 year-old woman with a history of cardiac problems develops hearing loss after a prolonged admission in hospital. Which drug may cause this?
A
Aminoglycosides ( eg. Gentamicin ), furosemide, aspirin, cytotoxic agents.
3
Q
Which drugs can cause erythema nodosum?
A
Penicillins
Sulphonamides
COCP