Pharmacology

Question 1

What are these drugs?
Omeprazole.
Lansoprazole.
Pantoprazole.
Rabeprazole.
Esomeprazole.

Answer 1

PPIs
Proton pump inhibitors (PPI) cause irreversible blockade of H+/K+ ATPase of the gastric parietal cell.

Examples include omeprazole and lansoprazole.

Adverse effects
hyponatraemia, hypomagnasaemia
osteoporosis → increased risk of fractures
microscopic colitis
increased risk of C. difficile infections

Question 2

What is Hydroxocobalamin?

Answer 2

Hydroxocobalamin is a manufactured version of the vitamin B12. It’s used to treat and prevent vitamin B12 deficiency anaemia,

Question 3

What class is ceftriaxone? (beginning with CEF)

Answer 3

Cephalosporin antibiotics

Question 4

What class are metoclopramide, domperidone, chlorpromazine?

Answer 4

Antiemetics (anti-sickness)

Question 5

What is octreotide?

Answer 5

Synthetic version of somatostatin (a somatostatin analogue) and slows down the production of hormones. This helps to control the symptoms of carcinoid syndrome and slow down the growth of the cancer.

Question 6

What is gabapentin?

Answer 6

Group of gabapentimoids
Used to treat neuropathic pain- sciatica
Can be addictive and drowsy

Question 7

What SSRI can be used for children?

Answer 7

Fluoxetine

Question 8

Signs and symptoms of wernickes?
CAN OPEN

Answer 8

C- confusion
A- ataxia
N- nystagmus

O- ophthalmoplegia
PE- peripheral
N- neuropathy