Pharmacology Flashcards
Indications for Acetaminophen?
Mild to moderate pain, fever
Contraindications for Acetaminophen?
Hypersensitivity, ETOH hepatatis, acute liver injury, acetaminophen induced liver disease
Dose of Acetaminophen?
Adult: 500-1000mg PO
PEDS: Under 30 kg 15mg/kg PO, 30-50 kg 500mg PO, over 50kg same as adult.
Adverse effects of Acetaminophen?
Uncommon but can include rash and hives, constipation develops with long term use.
Indications for ASA
CP or symptoms consistent with cardiac ischemia
Contraindications for ASA
Hypersensitivity, ASA allergic reaction, active or recent bleeding of any kind, pediatric patients with signs and symptoms consistent with viral illness.
Dosages of ASA
Adult 162mg PO.
MOA of ASA
Inhibits formation of thromboxane A2 which is a potent platelet aggregator and vasoconstrictor.
Adverse effects of ASA
Irritation of GI tract, antiplatelet effects may result in minor bruising or bleeding
What class of medication is Adenosine?
Anti-Arrhythmic
Adenosine indications
Conversion and termination of SVT’s
Adenosine contraindications
Hypersensitivity, second or third degree AV block, patients who have a known or suspected accessory pathway ( when presented with irregular or polymorphic WCT)
Procedure for the use of Adenosine?
Given very quickly in a proximal vein close to central circulation as possible (Right ACF), adenosine is chased with 20-30mL saline push at the top of the IV line. Maintaining pressure on the downstream plunger during administration. Ensure an ECG is being recorded during the admin of adenosine.
Dose of Adenosine
Adult: 6mg with 12 mg follow up if not successful during the first time. Both doses are rapid IV push.
Peds: Initial: 0.1mg/kg to maximum of 6mg IVP
Follow-Up: 0.2mg/kg to max dose of 12mg IVP.
MOA of Adenosine
Slows the conduction of impulses through the AV node by hyper polarizing the cell. Extending the refractory period and terminating the rhythm