Pharmacology Flashcards
With a majority of the antidepressant drugs, how long should you wait to see an effect?
6 weeks
Once the optimal effective dose has been reached for antidepressants, how long should you treat?
6 months
If you stop an antidepressant, how long is the washout phase?
3-6 weeks
List 5 SSRIs
Citalopram/Escitalopram
Sertraline
Fluoxetine
Paroxetine
List 5 SSRIs
Citalopram/Escitalopram
Sertraline
Fluoxetine
Paroxetine
What are common side effects of SSRIs?
Sexual dysfunction
Low libido
Prolonged ejaculation
Weight gain
List 3 SNRIs
Duloxetine
Venlafaxine/Desvenlafaxine
List 3 SNRIs
Duloxetine
Venlafaxine/Desvenlafaxine
Bupropion can also be used for what?
Smoking cessation
Describe the side effect profile of Bupropion?
Does NOT cause weight gain or sexual dysfunction
When should you avoid using Bupropion?
With eating disorders
If Bupropion is used with eating disorders, what does that do?
Lowers the seizure threshold
List 2 Serotonin Modulators
Mirtazapine
Trazodone
List 2 Serotonin Modulators
Mirtazapine
Trazodone
Trazodone can also be used as a?
Sleep aid
What is a serious side effect of Trazodone?
Priapism - extended erection
Mirtazapine can also be used to?
Stimulate appetite
List 2 suffixes and 1 TCA
–triptylines
–pramines
Doxepin
List 2 suffixes and 1 TCA
–triptylines
–pramine
Doxepin
What do TCAs treat?
Neuropathic pain
What are the 3 C’s often seen with TCA use?
Convulsions
Cardiac toxicity
Coma
List 3 MAOIs
Selegiline
Phenelzine
Tranylcypromine
List 3 MAOIs
Selegiline
Phenelzine
Tranylcypromine
If a patient is on an MAOI, what should they avoid and why?
Wine/cheese and other foods high in Tyramine
–> HTN crisis
What are 2 short acting Benzos?
Lorazepam
Alprazolam
What are 2 short acting Benzos?
Lorazepam
Alprazolam
What are 2 long acting Benzos?
Diazepam
Chlordiazepoxide
What are 2 long acting Benzos?
Diazepam
Chlordiazepoxide
List 2 time when Benzos might be used as treatment?
Abort panic attack
Alcohol withdrawal
What are the 2 FIRST LINE mood stabilizers?
Lithium
Valproic Acid
What are the 2 SECOND LINE mood stabilizers?
Quetiapine
Lamotrigine
What is the THIRD LINE mood stabilizer?
Carbamazepine
Lithium has a narrow therapeutic index. List 2 endocrine related side effects
Hypothyroidism
Nephrogenic Diabetes Insipidus
What anomaly can Lithium cause in utero?
Ebstein’s = abnormal tricuspid valve
What anomaly can Valproic Acid cause in utero?
Spina Bifida
What are 2 side effects of Valproic Acid?
Pancreatitis
Low platelets
Quetiapine can be used alone or with the 1st line mood stabilizers. What are 3 side effects?
Somnolence
Weight gain
QTC prolongation
Carbamazepine is a third line mood stabilizer. List 2 times it is more often used
Trigeminal Neuralgia
Absence Seizures
