Pharmacology

Question 1

With a majority of the antidepressant drugs, how long should you wait to see an effect?

Answer 1

6 weeks

Question 2

Once the optimal effective dose has been reached for antidepressants, how long should you treat?

Answer 2

6 months

Question 3

If you stop an antidepressant, how long is the washout phase?

Answer 3

3-6 weeks

Question 4

List 5 SSRIs

Answer 4

Citalopram/Escitalopram
Sertraline
Fluoxetine
Paroxetine

Question 5

List 5 SSRIs

Answer 5

Citalopram/Escitalopram
Sertraline
Fluoxetine
Paroxetine

Question 6

What are common side effects of SSRIs?

Answer 6

Sexual dysfunction
Low libido
Prolonged ejaculation
Weight gain

Question 7

List 3 SNRIs

Answer 7

Duloxetine
Venlafaxine/Desvenlafaxine

Question 8

List 3 SNRIs

Answer 8

Duloxetine
Venlafaxine/Desvenlafaxine

Question 9

Bupropion can also be used for what?

Answer 9

Smoking cessation

Question 10

Describe the side effect profile of Bupropion?

Answer 10

Does NOT cause weight gain or sexual dysfunction

Question 11

When should you avoid using Bupropion?

Answer 11

With eating disorders

Question 12

If Bupropion is used with eating disorders, what does that do?

Answer 12

Lowers the seizure threshold

Question 13

List 2 Serotonin Modulators

Answer 13

Mirtazapine
Trazodone

Question 14

List 2 Serotonin Modulators

Answer 14

Mirtazapine
Trazodone

Question 15

Trazodone can also be used as a?

Answer 15

Sleep aid

Question 16

What is a serious side effect of Trazodone?

Answer 16

Priapism - extended erection

Question 17

Mirtazapine can also be used to?

Answer 17

Stimulate appetite

Question 18

List 2 suffixes and 1 TCA

Answer 18

–triptylines
–pramines
Doxepin

Question 19

List 2 suffixes and 1 TCA

Answer 19

–triptylines
–pramine
Doxepin

Question 20

What do TCAs treat?

Answer 20

Neuropathic pain

Question 21

What are the 3 C’s often seen with TCA use?

Answer 21

Convulsions
Cardiac toxicity
Coma

Question 22

List 3 MAOIs

Answer 22

Selegiline
Phenelzine
Tranylcypromine

Question 23

List 3 MAOIs

Answer 23

Selegiline
Phenelzine
Tranylcypromine

Question 24

If a patient is on an MAOI, what should they avoid and why?

Answer 24

Wine/cheese and other foods high in Tyramine
–> HTN crisis

Question 25

What are 2 short acting Benzos?

Answer 25

Lorazepam
Alprazolam

Question 26

What are 2 short acting Benzos?

Answer 26

Lorazepam
Alprazolam

Question 27

What are 2 long acting Benzos?

Answer 27

Diazepam
Chlordiazepoxide

Question 28

What are 2 long acting Benzos?

Answer 28

Diazepam
Chlordiazepoxide

Question 29

List 2 time when Benzos might be used as treatment?

Answer 29

Abort panic attack
Alcohol withdrawal

Question 30

What are the 2 FIRST LINE mood stabilizers?

Answer 30

Lithium
Valproic Acid

Question 31

What are the 2 SECOND LINE mood stabilizers?

Answer 31

Quetiapine
Lamotrigine

Question 32

What is the THIRD LINE mood stabilizer?

Answer 32

Carbamazepine

Question 33

Lithium has a narrow therapeutic index. List 2 endocrine related side effects

Answer 33

Hypothyroidism
Nephrogenic Diabetes Insipidus

Question 34

What anomaly can Lithium cause in utero?

Answer 34

Ebstein’s = abnormal tricuspid valve

Question 35

What anomaly can Valproic Acid cause in utero?

Answer 35

Spina Bifida

Question 36

What are 2 side effects of Valproic Acid?

Answer 36

Pancreatitis
Low platelets

Question 37

Quetiapine can be used alone or with the 1st line mood stabilizers. What are 3 side effects?

Answer 37

Somnolence
Weight gain
QTC prolongation

Question 38

Carbamazepine is a third line mood stabilizer. List 2 times it is more often used

Answer 38

Trigeminal Neuralgia
Absence Seizures