Pharmacology Flashcards
-zosin
apha blocker q
-lol
beta blocker
-pril
ace inhibitor
-statin
lipid lowering drug
-ase, plase
thrombolytic
-parin
anticoagulant
-sone
corticosteriod
pharmacology
science of drugs used to prevent adn treat diseases
pharmacodynamics
study of how drugs act on an organism
pharmacokinetics
how the body handles drug over time
affinity
ability to attach to a receptor
efficacy
drugs ability to create an action once attached to a receptor
offical name of drugs/generic
USUALLY same as generic name and not capitalized
trade name
capitalized
pregnancy catagories
A- no risk
B-no stuides in human, animals show no riks
C-no human studies, animal shows risk
D- humans show risk but risks are worth it
X-risk clearly outweigh benefits
how many half lifes does it take to eliminate a drug
5
first pass metabolism
drugs absorbed through GI tract, happens in liver
intracellular fluid accounts for how much tbw
66%
crenaiton
dehydration, cells shrivel up like rasins
extracellular fluid TBW
33% accounts for both interstitial (25%) and intravascular fluid 75%
what makes up intravascular fluid
plasma, rbc, water, platlets, wbc
erythocytes
rbc
thrombocytes
platelets
Leukocytes
WBC
normal hemoglobin
13.5-17.5 males
12-16 female
hematocrit normal level
male 40-50
female 36-48
platlet count normal
150,000-400,000
normal wbc
5000-10,000
osmosis
movment of water from low solute concentration to high solute concentration
diffusion
molecules move from an area of high concentration to low concentration until equilibrium is reached
go from high concentration to low
carrier molecule
protein that combines with a solute molecule on one side of a membrane
two types
active and facilitated
active transport
moved against concentration gradiant
uses atp for energy
facilitated diffusion
moves substances into and out of cells from an area of higher concentration to an area of lower concentration
colloids
contain protein that are too large to pass through capillary membrane
crystalloids
dont contain large molecules
hypertonic
more solutes that 0.9
hypertonic fluid affect on cells
dehydrates them and crenates them and kills them
hypotonic fluid affect on cells
causes them to swell and burst (lyse)
IM injection max dose
5ml using a 19-21g needle
subq max dose
.05ml
23-25g needle
rate of infusion for fluid
ml x gtts
min