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Medicine > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

Side effects of N-acetylcysteine

A

Anaphylactoid reactions

- stop the infusion and continue at a slower rate

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2
Q

Uses of st john wart and side effects

A

Useful in mild depression
Works similar to ssri

Adverse effects- serotonin syndrome
Inducer of P450 system - decreased levels of warfarin and ciclosporin
Decrease effectiveness of COCP

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3
Q

Side effects of gentamicin

A

Ototoxicity

Nephrotoxicity

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4
Q

Macrolides examples

A

Erythromycin and clarithromycin

Can elongate QT interval

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5
Q

Tetracycline example

A

Doxycycline

Makes skin sensitivity to sun

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6
Q

Finisteride indications and side effects

A

BPH
Male pattern baldness

Impotence
Decrease libido
Gynaecomastia

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7
Q

Digoxin toxicity features

A

Generally unwell lethargy, nausea, vomiting, anorexia
Yellow-green vision
Arrhythmia
Gynaecomastia

No regulat monitoring of digoxin needed

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8
Q

Side effects of ACEi

A

Cough

Hyperkalaemia

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9
Q

Side effects of thiazides

A

Gout
Hypokalaemia
Hyponatraemia
Impaired glucose tolerance

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10
Q

Side effects of calcium channel blockers

A

Headache
Flushing
Ankle oedema

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11
Q

Beta blockers side effects

A

Bronchospasm
Fatigue
Cold peripheries

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12
Q

Which antibiotic is contraindicated in G6DP deficiency

A

Ciprofloxacin

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13
Q

Serptonin syndrome vs neuroleptic malignant

A

SS - neuromuscular excitation, hyperthermia, dilated pupils, altered mental status

NM - lead pipe rigidity - hyporeflexia
Haemodynamic instability

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14
Q

Drugs that cause lung fibrosis

A

Amiodarone
Cytotoxic agents
Anti-rheumatoid drugs - methotrexate, sulfalazine
Nitrofurantoin

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15
Q

Cocaine effects

A 
Coronary artery spasm 
HTN
QRS widening 
Seizures 
Pupil dailitation 
Hypertonia 
Hyperrefflexia

Management - benzos

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16
Q

Cocaine effects

A 
Coronary artery spasm 
HTN
QRS widening 
Seizures 
Pupil dailitation 
Hypertonia 
Hyperrefflexia

Management - benzos

17
Q

Cocaine effects

A 
Coronary artery spasm 
HTN
QRS widening 
Seizures 
Pupil dailitation 
Hypertonia 
Hyperrefflexia
Hyperthermia

Management - benzos

18
Q

TCA overdose management

A

Bicarbonate

19
Q

Salicylate management

A

Unitary alkalisatiin with IV bicarb

Haemodialysis

20
Q

Antidote of benzos

A

Flumaznil

Medicine (25 decks)

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