Oncology And Palliative Flashcards

1
Q

What is gardners syndrome?

A

Autosomal dominant colorectal cancer
Multiple polyps
Skull osteoma, thyroid cancer
A variant of FAP

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2
Q

AFP marker of what cancer?

A

Germ cell / testicular

Hepatobilliary

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3
Q

Calcitonin cancer marker?

A

Medullary thyroid

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4
Q

Cancer antigen 125 cancer marker?

A

Ovarian

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5
Q

Ca19-9 and ca15-3 cancer markers?

A

19 - pancreatic

13 - breast

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6
Q

CEA cancer marker?

A

Colorectal

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7
Q

Spinal cord compression management

A
Admit, bed rest and MRI whole spine in 24h
Dexamethosone 
Thromboprophylaxis 
Radiotherapy 
Decompressivr surgery
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8
Q

Superior vena cava obstruction management

A
Prop up 
O2
Dexamethasone 
CT scan 
Balloon venoplasty and stenting 
Chemo /radio
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9
Q

Malignant hypercalcaemia management

A

Aggressive rehydration

Bisphosphanates

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10
Q

Tumour lysis syndrome management

A

Prevent with hydration and allopurinol (in high risk patients)
Acute - allopurinol and fluids, consider sodium bicarbonate and dialysis

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11
Q

Conversion ratio of oral codeine to oral morphine

A

/10

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12
Q

Oral morphine to S/C morphine conversion

A

/2

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13
Q

Agents used in chemotherapy induced nausea

A

5HT3 receptor antagonist

Ondanserton

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14
Q

Anti-emetics used in GORD or gastric stasis

A

Metoclopramide

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15
Q

Sickness related to pressure in brain treatment

A

Dexamethasone

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16
Q

How to dose breakthrough morphine

A

A 6th of total daily morphine

17
Q

Conversion of morphine to diamorphine

A

/3

18
Q

Codeine to morphine conversion

A

/10

19
Q

Pain relief in impaired renal function

A

Fentanyl

20
Q

First line anti-emetic for intracranial causes of N+V

A

Cyclizine

21
Q

Good anti-emetic for gastric stasis

A

Metoclopramide

22
Q

Calcitonin is a marker for what?

A

Medullary thyroid cancer