Breast Surgery Flashcards

1
Q

Describe breast anatomy

A

Most of breast is adipose tissue
Nipple, with areola surrounding it
Behind the nipple = ducts lead into lobules
Lobules secrete milk, go through ducts and through openings of the nipple

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2
Q

What does triple assessment refer to?

A

Clinical examination
Imaging - US or mammography
Histology - fine needle aspiration or ore biopsy

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3
Q

What is a firbroadenoma? What are its features?

A

Common benign tumour of stromal/epithelial breast duct tissue

  • painless
  • smooth
  • round
  • well circumscribed
  • mobile
  • usually up to 3cm in diameter
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4
Q

Breast cyst features

A

Small
Mobile
Well-circumscribed
Possibly fluctuant

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5
Q

What is far necrosis and what are its features?

A

Benign lump caused by localised degeneration and scarring of fat tissue in the breast

Commonly triggered by localised trauma, radiotherapy or surgery causing an inflammatory response that results in fibrosis and necrosis

  • painless
  • firm
  • irregular
  • fixed in local structures
  • may be skin dimpling or nipple inversion
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6
Q

What is a lipoma? Its features?

A

Benign tumour of fat tissue, can occur anywhere in the body, including the breast

  • soft
  • painless
  • mobile
  • do not cause skin changes

Typically managed conservatively

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7
Q

What is a galactocele? Features?

A

Occur in women who are lactating
Often stop after breast feeding
Breast milk filled cysts that occur when the lactiferous duct is blocked preventing the gland from draining milk

  • firm
  • mobile
  • painless lump - usually beneath the areola
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8
Q

What is a phyllodes tumour? Features?

A

Rare tumours of the connective tissue (stroma) of the breast
Most commonly occur in 40-50 year old
Large and fast-growing
Can be benign or malignant

Treatment - surgical removal (wide excision)

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9
Q

What is mammary duct ectasia? Features?

A

Ectasia = dilation

Dilation with the large ducts of the breast, they can become clogged and inflamed leading to intermittent discharge from the nipple (green, grey, white). Occurs in postmenopausal women usually.

Can also have nipple retraction or inversion

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10
Q

What is an intraductal papilloma? Typical presentation?

A

Warty lesion that grows in one of the ducts
Proliferation of epithelial cells
Benign tumours but can be associated with breast cancer

Typically clear or blood-stained nipple discharge 
Most commonly 34-55 years old 
Often asymptomatic 
Tenderness 
Palpable lump
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11
Q

Most common type of breast cancer

A

Invasive ductal carcinoma

Re-named no specific type

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12
Q

Risk factors for breast cancer

A
Female obviously 
Increased oestrogen expsorue - early periods, late menopause
COCP - small risk but stops 10 years after taking it
Obesity 
Smoking 
More dense breast tissue 
Family history - first-degree
HRT - especially combined
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13
Q

Describe hormonal therapy of breast cancer

A

Anti-Oestrogen therapy - tamoxifen (given to those who have cancers that are oestrogen sensitive)
Post-menopausal = aromatase inhibitors (anastrozole)

Biological therapy - tratuzumab - (herceptin) if HER2 sensitive

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14
Q

Can fibroadenomas be surgically removed?

A

Yes if >3cm (or causing discomfort etc.)
Via excision biopsy

If <3 cm then it could be observation and simple advice be enough.

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15
Q

Are young women usually given mammograms

A

No, as ineffective due to dense breasts

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16
Q

What is given after wide local excision of breast cancer?

A

Radiotherapy to prevent recurrence

17
Q

Breast cancer with clinically palapable lymphadenopathy, management

A

US-guided biopsy with Axillary node clearance at primary surgery

18
Q

Who does mastitis commonly affect?

A

Breastfeeding women

19
Q

Management of mastitis

A

Continue breast feeding

If not improving within 24 hours, symptoms not resolving or if culture indicates infection

Flucloxacillin for 10-14 days
If untreated - may develop into abscess

20
Q

What is letrozole?

A

An aromatase inhibitor, used in oestrogen receptor sensitive cancer in post menopausal women

21
Q

Tender breast lump in a 32 year old breast feeding woman

A

Breast abscess (likely at risk of mastitis, leading to abscess if not treated)

22
Q

Creamy nipple discharge originating from multiple ducts in a 53 year old associated with nipple inversion

A

Duct ectasia

23
Q

When does duct ectasia occur?

A

During menopausal period

As ducts shorten they may contain insipiated material

24
Q

52 year old lady with an episode of nipple discharge, usually clear, from a single duct. Contains some blood.

Also a young woman with blood stained nipple discharge. Not usually a palpable mass

A

Intraductal papilloma

25
Q

What is the commonest cause of blood stained nipple discharge in younger women?

A

Intraductal papilloma

26
Q

Differentiating between pagets disease of the nipple and eczema of the nipple

A

Pagets- involves nipple, spreads to areola later. Opposite in eczema

27
Q

What is fibroadenosis?

A

Most common in middle aged women
Lumpy breasts that may be painful
Syptoms worsen prior to menstruation

28
Q

Describe breast cancer screening

A

Mammogram every 3 years to women aged 50-70 years

29
Q

Inflammatory breast cancer presentation

A

Atypical appearance - progressive erythema oedema in the absence of infection signs like fever, discharge or elevated WCC and CRP

Elevated CA 15-3

30
Q

Duct ectasia vs intraductal papilloma presentation

A

Ectasia - older
pap - younger
Ectasia = Green, brown discharge, smokers
Pap = blood stained discharge, no palpable lump

31
Q

Side effects of aromatase inhibitors

A

Osteoporosis
Hot flushes
Insomnia
Arthralgia

32
Q

Tamoxifen side effects

A

Vaginally bleeding, amenorrhoea
Hot flushes
VTE
Endometrial cancer

33
Q

Halo sign on mammogram is associated with what?

A

Breast cyst