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Last Ditch > Pharmacology > Flashcards

Pharmacology Flashcards

0
Q

Acute gout

A

Colchicine

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1
Q

Allopurinol inhibits

A

Xanthine oxidase

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2
Q

Given in combination with Imipenem

A

Cilastatin

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3
Q

Drug for Parkinson’s disease

A

Tacrine

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4
Q

Inhibitor of thromboxane A2

A

Aspirin

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5
Q

DOC for CML

A

Busulfan

SE: pulmonary fibrosis

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6
Q

Treatment for glaucoma

A

Pilocarpine

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7
Q

Carbonic anhydride used in glaucoma

A

Acetazolamide

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8
Q

MOA of Orlistat

A

Reversible inhibitor of lipase

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9
Q

Phosphate analogue to treat CMV

A

Foscarnet

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10
Q

Chemotherapeutic agent of choice in colon CA

A

5-FU

MOA: thymydilate synthase inhibitor

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11
Q

NSAID protective for colon CA

A

Aspirin

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12
Q

Gray baby syndrome

A

Chloramphenicol

Other SE: aplastic anemia

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13
Q

SE of tetracycline

A

Teeth discoloration
Epiphyseal plates
Milk alkali syndrome

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14
Q

Milk alkali syndrome

A

Antacids + Tetracycline

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15
Q

DOC for cholera

A

Tetracycline

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16
Q

DOC for leptospirosis

A

Doxycycline

Also used for Chlamydia

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17
Q

Red man syndrome

A

Vancomycin

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18
Q

Causes gingival hyperplasia

A

Chronic phenytoin toxicity

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19
Q

Anti-hypertensive contraindicated in pregnancy

A

ACE inhibitors

It causes fetal renal agenesis

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20
Q

SE of ACE inhibitors

A

Cough

Due to Bradykinin

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21
Q

SE: Ethambutol

A

Barrel-vision

Optic neuritis

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22
Q

Drug that causes peripheral neuropathy? Treatment?

A

INH

Treatment: Pyridoxine

23
Q

Dissociative anesthetic

24
Q

Malignant hyperthermia

A

Succinylcholine + Halothane

Succinylcholine is a neuromuscular blocker
DOC: Dantrolene

25
Q

Twilight sleep

A

Sedative + Scopolamine

Scopolamine (anti cholinergic drug): used for motion sickness

26
Q

DOC for vertigo

A

Beta-histine

27
Q

Drugs used for motion sickness

A

Meclizine

Scopolamine

28
Q

Chemodrug that causes cardiac toxicity

A

Doxurubicin

29
Q

Hemorrhagic cystitis

A

Cyclophosphamide

30
Q

DOC for Absence seizure

A

Ethosuximide

MOA: decrease calcium

31
Q

Bronchodilator used to reduce uterine contractions in premature labor

A

Ritodrine

Others: Terbutaline

32
Q

Pre-op drug to control thyrotoxicosis

A

Propanolol

Alternative: Lugol’s iodine (to decrease vascularity and size of the gland)

33
Q

Drug that penetrate the burn eschar

A

Mafenide acetate

34
Q

Toxic metabolite of INH

A

Acetyl hydrazine

35
Q

Asthma drug that has a narrow therapeutic index

A

Aminophyline
(Theophylline)

Has many drug interactions

36
Q

DOC for vomiting in pregnancy

A

Hyperemesis gravidarum

Give Pyridoxine (vitamin B6)

37
Q

Magnesium sulfate level where patellar reflex disappear

38
Q

Role of magnesium sulfate in pre-eclampsia

A

Anti-convulsant

39
Q

Antidote for organophosphate poisoning after 12 hours

A

Acute: Atropine
Chronic: Pralidoxime

40
Q

DOC for post-chemo vomiting

A

Ondansetron

41
Q

DOC for beta blocker overdose

42
Q

Antidote for paracetamol toxicity

A

N-acetylcysteine

43
Q

DOC for Tourette’s syndrome

A

Haloperidol

44
Q

MOA of coccaine

A

Inhibits diffusion and re-uptake via NET and DAT in synaptic cleft

NET: NE transport
DAT: Dopamine agonist transport

45
Q

Mechanism of interaction in milk-alkali syndrome

46
Q

Preoperative anesthesia use of atropine

A

Decrease respiratory secretions

47
Q

Why is atropine added to diphenoxylate

A

To prevent abuse

48
Q

DOC for salmonella carrier

A

Ciprofloxacin

Reservoir for S. typhi: gallbladder

49
Q

Somatren is a

A

GH analogue

50
Q

DOC for extraluminal amoebiasis

A

Metronidazole

51
Q

Luminal amoebacide

A

Diloxanide

52
Q

DOC for diabetic gastroperesis

A

Metoclopramide

53
Q

Anti thyroid drug for pregnancy

54
Q

Second line anti-TB drug which is a structural analogue of INH

A

Ethionamide

Last Ditch (14 decks)

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