Pharmacology Flashcards
What are the symptoms associated with opioid withdrawal that you would want to prescribe a prn for?
- muscle aches
- restless legs
- nausea
- diarrhea
- agitation
What are the medications you would prescribe for opioid withdrawal as prn for the following symptoms?
- muscle aches
- restless legs
- nausea
- agitation
- diarrhea
- NSAIDs like ibuprofen for muscle aches
- gabapentin for restless legs
- zofran for nausea
- clonidine for agitation
- immodium/loperamide for diarrhea
Effexor is aka and has what MOA?
- venlafaxine
- SNRI
Celexa is aka and has what MOA?
- citalopram
- SSRI
Fanapt is aka and has what MOA?
- iloperidone
- antagonist of 5HT2A and D2 receptors
- antipsychotic
Fetzima is aka and has what MOA
- levomilnacipran
- exact MOA is unknown, but thought to be SSRI/SNRI
Before starting ziprasidone, what should be checked?
- EKG if the patient has cardiac disease
* can prolong QT
Before starting venlafaxine, what should be checked?
- BP
* venlafaxine can raise bp due to increase norepinephrine
Before prescribing valproic acid, what should be checked?
- CBCs for platelets
- pregnancy for females *teratogenic
- LFTs
Before starting TCAs, what should be checked?
- ECG if patient has cardiac disease or if the patient is 50 >
When to recheck LFTs with a new patient on depakote?
- 2 weeks, then 6 months, then annually
When to recheck CBC in a patient new on depakote?
- annually
When to recheck EKG for a patient started on ziprasidone aka Geodon?
- high risk patients need a new EKG after reaching full dose of ziprasidone
When to recheck ECG for a patient on TCAs?
- annually if over 50 or have cardiac disease
If you change a dose of depakote, when should you check depakote blood level?
- 1 week after dose change to make sure it is in therapeutic range
Before starting topiramate, what should be checked in a patient?
- bicarbonate level
How often should the bicarbonate level be checked with a patient on topiramate?
- annually
Before prescribing a stimulant, what should be checked?
- EKG if a patient has cardiac disease
Before prescribing risperdal, what should you test for ?
- fasting glucose
- lipids
What should you test for before prescribing phenelzine?
- LFTs
When should you recheck for LFTs in a new patient with phenelzine?
6-12 months after and then if liver dysfunction occurs
What should you check for before prescribing mirtazapine?
- BMI
- fasting lipids
When should you recheck for fasting lipids on a patient on mirtazapine?
- after 1 year and then after 5 years if normal
MOA of suboxone
- partial mu opioid agonist due to buprenorphine effect
- opioid antagonist due to naloxone effect
