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Psychiatry > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

What are the symptoms associated with opioid withdrawal that you would want to prescribe a prn for?

A
  • muscle aches
  • restless legs
  • nausea
  • diarrhea
  • agitation
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2
Q

What are the medications you would prescribe for opioid withdrawal as prn for the following symptoms?

  • muscle aches
  • restless legs
  • nausea
  • agitation
  • diarrhea
A
  • NSAIDs like ibuprofen for muscle aches
  • gabapentin for restless legs
  • zofran for nausea
  • clonidine for agitation
  • immodium/loperamide for diarrhea
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3
Q

Effexor is aka and has what MOA?

A
  • venlafaxine

- SNRI

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4
Q

Celexa is aka and has what MOA?

A
  • citalopram

- SSRI

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5
Q

Fanapt is aka and has what MOA?

A
  • iloperidone
  • antagonist of 5HT2A and D2 receptors
  • antipsychotic
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6
Q

Fetzima is aka and has what MOA

A
  • levomilnacipran

- exact MOA is unknown, but thought to be SSRI/SNRI

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7
Q

Before starting ziprasidone, what should be checked?

A
  • EKG if the patient has cardiac disease

* can prolong QT

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8
Q

Before starting venlafaxine, what should be checked?

A
  • BP

* venlafaxine can raise bp due to increase norepinephrine

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9
Q

Before prescribing valproic acid, what should be checked?

A
  • CBCs for platelets
  • pregnancy for females *teratogenic
  • LFTs
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10
Q

Before starting TCAs, what should be checked?

A
  • ECG if patient has cardiac disease or if the patient is 50 >
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11
Q

When to recheck LFTs with a new patient on depakote?

A
  • 2 weeks, then 6 months, then annually
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12
Q

When to recheck CBC in a patient new on depakote?

A
  • annually
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13
Q

When to recheck EKG for a patient started on ziprasidone aka Geodon?

A
  • high risk patients need a new EKG after reaching full dose of ziprasidone
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14
Q

When to recheck ECG for a patient on TCAs?

A
  • annually if over 50 or have cardiac disease
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15
Q

If you change a dose of depakote, when should you check depakote blood level?

A
  • 1 week after dose change to make sure it is in therapeutic range
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16
Q

Before starting topiramate, what should be checked in a patient?

A
  • bicarbonate level
17
Q

How often should the bicarbonate level be checked with a patient on topiramate?

A
  • annually
18
Q

Before prescribing a stimulant, what should be checked?

A
  • EKG if a patient has cardiac disease
19
Q

Before prescribing risperdal, what should you test for ?

A
  • fasting glucose

- lipids

20
Q

What should you test for before prescribing phenelzine?

A
  • LFTs
21
Q

When should you recheck for LFTs in a new patient with phenelzine?

A

6-12 months after and then if liver dysfunction occurs

22
Q

What should you check for before prescribing mirtazapine?

A
  • BMI

- fasting lipids

23
Q

When should you recheck for fasting lipids on a patient on mirtazapine?

A
  • after 1 year and then after 5 years if normal
24
Q

MOA of suboxone

A
  • partial mu opioid agonist due to buprenorphine effect

- opioid antagonist due to naloxone effect

25
Q

What is suboxone used to treat?

A
  • short-term opioid withdrawal induction treatment

- opioid dependence maintenance

26
Q

What is the combo generic drugs that make up suboxone?

A
  • buprenorphine and naloxone
27
Q

Why is sublingual preferred over buccal administration for suboxone?

A
  • the naloxone concentration will be higher when administered buccally and we do not want to precipitate a withdrawal, so we give it sublingually
28
Q

Why does buprenorphine work for detoxing people with opioid addiction?

A
  • has a higher affinity to bind to the mu opioid receptor site and will not cause euphoria because of the ceiling effect.
29
Q

What is the ceiling effect?

A
  • buprenorphine reaches a steady level and does not linearly increased like full opioid agonists
30
Q

What should be checked before starting olanzapine in a patient?

A
  • fasting lipids

- BMI

Psychiatry (15 decks)

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