Pharmacological therapy: Nonselective adrenergic agonists

Question 1

Adrenaline - epinephrine

Answer 1

• rarely used treatmentglaucoma

- last line agents systemic side effect profil

Question 2

MOA adrenaline

Answer 2

• alpha B agonist act

- increase outflow aq humour through trabecular meshwork + uveoscleral pathway

Question 3

adm of adrenaline

Answer 3

• instilled twice daily + reduce IOP

Question 4

Local adverse effect

Answer 4

• mydriasis
• conjunctival hyperamia
• ocular irritation
• aphakic patienta shouldnt used these - reversible cytstoid macular oedema

Question 5

Adrenaline should not be used in patients

Answer 5

• narrows angles - cause acute angle closure

Question 6

systemic side effects

Answer 6

• palpitations
• increased BP
• arrhytmia

Question 7

should be used in caution with

Answer 7

• CV disease
• cerebrovascular disease
• hyperthyroidism

Question 8

Counsel patients

Answer 8

• nasloacrimal technique - decrease systemic effects