Pharmacological Management Flashcards
What drugs decrease blood pressure and after load by suppressing the enzyme that converts angiotensin I to angiotensin II
Angiotensin-converting enzyme (ACE) inhibitor agents
Caroten (captorpril) vasotec (enalapril)
What drug decreases blood pressure by blocking angiotensin II receptors which limit vasoconstriction and stimulation of vascular tissue?
Angiotensin II Receptor Antagonist agents
What drugs inhibit platelet aggregation and clot formation?
Antithrombotic (antiplatelet) agents - post mi, a fib, prevent arterial thrombus formation - Bayer (Asprin)
These are indications for what drug post percutaneous transluminal coronary angioplasty and coronary bypass graft surgery, prevention of venous thromboembolism and cardiovascular events in pt with a fib and prosthetic heart valves
Anticoagulant agents
What drugs inhibit enzyme action in cholesterol synthesis, break down LDL, decrease triglyceride levels, and inc HDL levels?
Antihyperlipidemia agents- Lipitor (statins)
What drugs dec myocardial oxygen demand and BP by decreasing HR and contractility?
Beta blocker agents - tenormin (atenolol)
What drugs dec the entry of calcium into vascular smooth muscle cells resulting in diminished myocardial contraction, vasodilation, and decreased oxygen demand of the heart?
Calcium channel blocker agents - norvasc (amlodipine), procardia ( nifedipine)
What drugs inc the excretion of sodium and urine. This causes a reduction in plasma volume which decreases BP.
Diuretic agents - thiazide: diuril (chlorothiazide)
What drugs decrease ischemia through smooth muscle relaxation and dilation of peripheral vessels?
Nitrate agents - nitrostat nitroglycerin
What drugs are indicated for HF and a fib, and inc the force of myocardial contraction, slow the hr, dec conduction velocity through the av node, and dec the degree of activation of the sympathetic nervous system?
Positive inotropic agents - lanoxin (digoxin)
Watch for bradycardia
What drugs are indicated for acute MI, PE, ischemic stroke, arterial or venous thrombosis, by converting plasminogen to plasmin. Plasmin breaks through the clot and allow occluded vessels to reopen
Thrombolytic agents - linlytic (urokinase) activase (alteplase)
What drug reduces peripheral vascular tone. This action causes dilation of arterioles and veins and thus reduces hypertension.
Alpha Adrenergic Antagonist Agents
Cardura (doxazosin) minipress (prazosin)
