Pharmacokinetics & Pharmacodynamics

Question 1

four process of pharmacokinetics

Answer 1

absorption
distribution
metabolism/biotransformation
elimination

Question 2

it is the rate at which a drug leaves it site of administration and the extent to which absorption occurs

Answer 2

absorption

Question 3

in absorption, it is expressed as the fraction of administered drug to give access or teaches to our systemic circulation

Answer 3

bioavailability

Question 4

in absorption, it looks if comparable the efficacy and safety of drugs

example: 2 drugs, branded and generic drugs have the same effectivity

Answer 4

bioequivalent

Question 5

five (5) factors that affects absorption

Answer 5

administered route
food or fluid administered with drugs
dosage formulation
status of absorptive surface
status of GI motility

Question 6

three (3) routes of administration

Answer 6

enteral route
parenteral
topical

Question 7

in routes, this is absorb into the systemic circulation and it involves our esophagus, stomach, small and large intestines

this can be oral, sublingual, rectal and buccal

Answer 7

enteral route

Question 8

in routes, this is administered by injection or catheter

this can be intravenous, subcutaneous, intramuscular etc..

Answer 8

parenteral route

Question 9

in routes, this administration is through body surface (skin)

this can be cream, lotion, gel or ointments that we can use in our skin, eyes, nose and vagina

Answer 9

topical route

Question 10

it is the transport of drugs in the body by blood stream

this can be fast and slow

Answer 10

distribution

Question 11

heart, liver, kidney and brain ; ____ distribution

Answer 11

heart, liver, kidney and brain ; fast distribution

Question 12

muscle, skin and fat ; ____ distribution

Answer 12

muscle, skin and fat ; slow distribution

Question 13

it is the biological transport of a drug into an inactive metabolite, a more soluble compound or more potent metabolite

the liver is the main organ

Answer 13

metabolism or biotransformation

Question 13

it is the biological transport of a drug into an inactive metabolite, a more soluble compound or more potent metabolite

the liver is the main organ

Answer 13

metabolism or biotransformation

Question 14

it is the elimination of drug from the body

the kidney is the main organ

Answer 14

elimination

Question 15

it is what drug does to our body

Answer 15

pharmacodynamics

Question 16

it is what the body does to the drugs

Answer 16

pharmacokinetics

Question 17

in pharmacodynamics, it is the biological, mechanical mechanism, chemical procedures reaction to living organism

Answer 17

drug action

Question 18

in drug actions, it stimulates and active the receptor

Answer 18

agonist

Question 19

in drug actions, it stops the agonist from stimulating receptor

Answer 19

antagonist

Question 20

in pharmacodynamics, it is the physiological reaction of the body to the drug

Answer 20

drug effect

Question 21

in pharmacodynamics, it is the way which drug can produce therapeutic effects

Answer 21

mechanism of action