Pharmacokinetics: Module 1-Section 04

Question 1

What is pharmacokinetics?

Answer 1

Refers to the movement of a drug into, through, and out of the body.

Question 2

What are the 3 routes of administration?

Answer 2

Topical, Enteral, Parenteral

Question 3

What is a topical route?

Answer 3

Drugs that are applied through the skin, on the skin or inhaled.

Question 4

What is a enteral route?

Answer 4

Drugs administered through the GI tract, entering through the mouth or an artificial opening. Such as, mouth, rectum or sublingual/buccal.

Question 5

What is a parenteral tract?

Answer 5

A drug administered bypassing the GI tract. Such as intravenous, intramuscular, and subcutaneous.

Question 6

What is systemic effect?

Answer 6

A descriptor used to indicate something that affects the whole body or multiple organ systems.

Question 7

What is bioavailability?

Answer 7

The fraction of an administered dose that reaches the blood in an active form.

Question 8

What is the A in ADME?

Answer 8

Absorption

Question 9

What is the D in ADME?

Answer 9

Distribution

Question 10

What is the E in ADME?

Answer 10

Excretion

Question 11

What is the M in ADME?

Answer 11

Metabolism

Question 12

What is absorption?

Answer 12

The movement of a drug from the site of administration into the blood.

Question 13

What is distribution?

Answer 13

The movement of a drug from the blood to the side of action and other tissues.

Question 14

What is metabolism?

Answer 14

The conversion of a drug to a different chemical compound in order to eliminate it.

Question 15

What is excretion?

Answer 15

It refers to moving the drug and it’s metabolites out of the body.

Question 16

What are 5 factors for drug response variation?

Answer 16

Genetics, Environment, Disease States, Physiological States, Presence of Other Drugs