Pharmacokinetics/dynamics Flashcards
The ability of a drug to move into solution
Dissolution
3 different names a drug will acquire during the drug development process
- Chemical name
- Generic name
- Brand or trade name
Drug route of administration affects the _________ and _________ of ____________ of a drug.
Rate and extent of absorption
What are the 3 routes of drug administration?
Enteral
Parenteral
Topical
Enteral routes of drug administration include:
Liquids (fastest) Elixirs Syrups Suspensions Solutions Powders Capsules Tablets Enteric coated (slowest) Sublingual and Buccal
Any drug that enters the entire alimentary canal (oral or suppository) is considered which route of administration?
Enteral
Drugs administered under the tongue or on the cheek and are absorbed directly into vascular tissue.
Sublingual and Buccal
Drugs that are absorbed through the capillary system, going right into systemic circulation are administered by which route?
Parenteral
Drugs that are absorbed through the skin, including respiratory lining
Topical
Phase of pharmacokinetics that involves movement of a drug from the site of administration into the bloodstream for distribution to the tissues
Absorption
Two drugs that have the same concentration and bioavailability
Bioequivalent drugs
Phase of pharmacokinetics that involves the movement of a drug to the body’s tissues
Distribution
Drug traveling in circulation is bound to proteins in blood
Protein binding
Only unbound drugs are free to produce a therapeutic effect.