Pharmacokinetics

Question 1

Ability of the drug to cross cell membrane is influenced by its solubility in water or fat, its size and shape

Answer 1

Absorption

Question 2

only small water-soluble molecules which flow through hydrophilic pores

Answer 2

Filtration

Question 3

diffusion i.e. from high concentrations to low concentrations

Answer 3

Passive transport

Question 4

energy and carriers are required to move non-fat soluble substances across the cell membrane e.g. against concentration gradient

Answer 4

Active transport

Question 5

major organs n blood vessels

Answer 5

Central Compartment

Question 6

skin and fat stores

Answer 6

Peripheral compartment

Question 7

Deactivated Metabolites

Answer 7

Excreted from the body

Question 8

Activated Metabolites

Answer 8

Exert effects on tissues

Question 9

Metabolism of a drug and its passage from the liver into the circulation

Answer 9

First Pass Effect

Question 10

Mucosa of the stomach, mouth, small intestine, or rectum; blood vessels in the muscles or subcutaneous tissues; or dermal layers

Answer 10

Absorption

Question 11

Circulatory system, through capillaries and across cell membranes

Answer 11

Distribution

Question 12

Liver

Answer 12

Metabolism

Question 13

Kidneys, sweat glands, lungs, or intestines

Answer 13

Excretion

Question 14

how the drug affects the body;
science dealing with interactions between the chemical components of living systems and the foreign chemicals, including drugs that enter those systems

Answer 14

Pharmacodynamics