Pharmacokinetic Drug-drug interactions (Excretion) Flashcards
1
Q
Aspirin + Urinary alkalinizer
Barbs, NSAIDs, Amphetamine + Urinary modification
A
Alteration of pH
2
Q
Penicillin + Probenecid
NSAIDs + Lithium
A
Alteration of active transport
3
Q
Digoxin + Quinidine
Alteration of…
A
Alteration of drug transport
3
Q
Aspirin + Urinary alkalinizer
A
Acid + Polar/Ionized = excreted
4
Q
Barbs, NSAIDs, Amphetamine + Urinary modification
A
Excreted
5
Q
Penicillin + Probenecid
A
Probenecid blocks active tubular secretion of penicillin
6
Q
NSAIDs + Lithium
A
NSAIDs inhibit renal Li excretion
7
Q
Digoxin + Quinidine
A
Quinidine inhibits renal excretion of digoxin