Pharmacodynamic Drug-Drug interactions (Synergism) Flashcards
cidal + cidal
Synergism
All cell wall synthesis inhibitors, DNA inhibitors except , are -cidal
Folate inhibitor
Anti-TB (except Ethambutol)
All protein synthesis inhibitors are
Static
Sulfomethoxazole +
Trimethoprim (Bactrim, Septrim K)
Sulfadoxine +
Pyrimethamine (Fansidar)
Penicillin +
Aminoglycoside
Sulfomethoxazole + Trimethoprim
static + static = cidal
Sulfadoxine + Pyrimethamine
static + static = cidal
Penicillin + Aminoglycoside
cidal + cidal = static
SulfadiaZene + Pyrimethamine
ProphylaXis for cerebral toXoplasmosis
For UTI, prophylaxis of PCP
Sulfomethoxazole + Trimethoprim (Bactrim, Septrim K)
Tx. for chloroquine resistant falcifarum malaria
Sulfadoxine + Pyrimethamine (Fansidar)